pathologic response

PURPOSE Recent studies have highlighted that the p53 codon 72 polymorphism plays a crucial role in modulating wild-type p53 apoptotic capacity, and as such may influence the response to chemotherapy. Thus, the purpose of this study was to investigate whether the p53 codon 72 polymorphism might influence pathologic response to neoadjuvant chemotherapy in primary breast cancer. EXPERIMENTAL DES...

متن کامل

The PERK Arm of the Unfolded Protein Response Regulates Mitochondrial Morphology during Acute Endoplasmic Reticulum Stress

2018

Justine Lebeau Jaclyn M. Saunders Vivian W.R. Moraes Aparajita Madhavan Nicole Madrazo Mary C. Anthony R. Luke Wiseman

Endoplasmic reticulum (ER) stress is transmitted to mitochondria and is associated with pathologic mitochondrial dysfunction in diverse diseases. The PERK arm of the unfolded protein response (UPR) protects mitochondria during ER stress through the transcriptional and translational remodeling of mitochondrial molecular quality control pathways. Here, we show that ER stress also induces dynamic ...

متن کامل

Impact of pathologic tumor response in the treatment of gastric cancer

Journal: :Translational Gastroenterology and Hepatology 2016

متن کامل

Understanding patterns of pathologic response following neoadjuvant immunotherapy for solid tumors

Journal: :Annals of Oncology 2018

متن کامل

survival rate of breast cancer based on geographical variation in iran, a national study

Journal: :iranian red crescent medical journal 0

mohammad movahedi cancer research centww, shohidavejw{{ ihyusmt}aovimd{sumrwcience, ir iran +98-2122748001, [email protected]; epidemiology department, school of public health, shahidbeheshti university of medical science, ir iran shahpar haghighat epidemiology department, school of public health, shahidbeheshti university of medical science, ir iran; quality of life in cancer department, iranian center for breast cancer, acecr, ir iran maryam khayamzadeh cancer research centww, shohidavejw{{ ihyusmt}aovimd{sumrwcience, ir iran +98-2122748001, [email protected] afshin moradi cancer research centww, shohidavejw{{

background breast cancer is the most common cancer among women worldwide. based on the latest iranian national cancer department report, the total number of women registered with breast cancer was 6976 cases during 2007. five year survival is one of the indicators used for evaluation of the quality for care to different types of malignancies including breast cancer. objectives the aim of this s...

متن کامل

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید