To facilitate the diagnosis of recent rubella infection, rubella haemagglutination inhibiting antibody has been determined in four fractions obtained by Sephadex G-200 gel filtration of samples of serum. All the 21 samples collected at the convalescent stage of the disease had varying proportions of haemagglutination inhibiting antibody in fraction 1, representing the major portion of IgM antib...

Inoculation of female rabbits with `coagulo-prostatic fluid' (CPF), a secretory-specific autoantigen of male accessory sexual glands, permitted the identification by the methods of gel precipitation and passive haemagglutination of tissueand species-specific antibodies to CPF. Subsequent mating of females with high titres of circulating antibodies to CPF at the time of coitus resulted in impair...

Mild detergent treatment (0.1% Sarkosyl-0.1% beta-mercaptoethanol) of Dane particle-rich fraction from human serum resulted in the release of core particles together with HBe antigen activity when examined by the reversed passive haemagglutination method. Furthermore, when the core particles isolated by the above procedure were exposed to stronger detergent (1% Sarkosyl-0.1% beta-mercaptoethano...

Haemagglutination reactions for the diagnosis of syphilis were first reported by Blumenthal (1932) and Bachmann (1932), who used an extract of syphilitic liver as the antigen. However, the test yielded both false positive and false negative reactions, rendering it of no diagnostic value. An agglutination test with suspensions of Reiter treponemes was used for testing cerebrospinal fluid by Roem...

Passive haemagglutination and IEOP have been used both to detect and to measure tetanus antitoxin in human donor sera. Forty percent of blood donors had detectable antitoxin but only 9% had levels suitable for production of human antitetanus immuoglobulin (larger than or equal to 2 IU/ml). The incidence of high titre antitoxin was significantly greater in men and was unrelated to the ABO blood ...