PURPOSE Most deep brain stimulation targets for movement disorders were derived from effective ablative surgery targets. Similarly effective lesion targets for epilepsy control may help refine brain stimulation targeting for epilepsy. A literature review of past stereotactic lesions for epilepsy treatment was performed to provide historical context and possible anatomical guidance for current a...

Bathing-related epilepsy (BRE), which is also known as water immersion epilepsy, is a rare, benign, reflex epilepsy. It presents with focal seizures that occur during bathing with hot water and has a favorable prognosis (1). The exact mechanism underlying these seizures is unknown (1). This epilepsy is frequently confused with hot water epilepsy (HWE) and is generally seen during childhood and ...

With the growth in antiepileptic drug treatment, the question arises as to what extent we are merely treating the symptom (i.e. the seizures) rather than the underlying disease process (i.e. epileptogenesis). Epileptogenicity can be considered as the process whereby structural and functional changes occur following an insult that in some cases result in epilepsy. Epileptogenicity also describes...

BECTS is characterized by the presence of simple partial motor seizures in the face and/or oropharynx, with or without sensory symptoms and often with secondary generalization. These seizures tend to occur more often during sleep or drowsiness. According to some authors, generalized seizures prevail over other types particularly among children aged five or less. The purpose of this study is to ...

Very high prevalence rates of epilepsy have been found in some developing countries. The Zay Society of Ethiopia was screened for epilepsy during a door-to-door survey and after neurological assessment, a prevalence of 29.5/1000 was found. Almost all the cases had primary generalised epilepsy in contrast to the predominance of partial epilepsy found elsewhere. Due to its historical isolation, e...

[TOP] Responsive neurostimulation (RNS) may be considered medically necessary for patients with partial epilepsy who meet ALL of the following criteria:  Are 18 years or older.  Have a diagnosis of partial-onset seizures with 1 or 2 well-localized seizure foci identified.  Have an average of 3 or more disabling seizures (e.g., motor partial seizures, complex partial seizures, or secondary ge...

Extirpation of a large portion of the liver in rats results in a marked decrease in the plasma prothrombin. The plasma prothrombin level gradually returns to normal during the period required for restoration of the liver to its normal weight. The decrease in prothrombin incident to partial hepatectomy supports the thesis that the liver is concerned in the manufacture of plasma prothrombin.

A number of clinical trials that test the efficacy and safety of the newer antiepileptic drugs (AEDs) have recently been concluded. Two dose-response trials in inpatients with refractory partial seizures and outpatients with newly diagnosed partial epilepsy established the efficacy of gabapentin as monotherapy. Lamotrigine was found to have efficacy similar to that of phenytoin and carbamazepin...

The aim was to examine the occurrence of benign partial epilepsy in infancy (BPEI). BPEI was defined as epilepsies with complex partial seizures (CPS) or secondary generalised seizures (SGS), or both, compatible with the following characteristics: normal development before and after onset, no underlying disorders, normal interictal electroencephalograms (EEGs), and good response to treatment. A...

An increasing number of infantile epilepsy syndromes have been recognized. However, a significant number of infants (children aged 1-24 months) do not fit in any of the currently used subcategories. This article reviews the clinical presentation, electroencephalographic findings, evolution, and management of the following entities: early infantile epileptic encephalopathy, early myoclonic epile...