This study described the structural characterization of Pakistani HCV NS3 GT3a in parallel with genotypes 1a and 1b NS3. We investigated the role of amino acids and their interaction patterns in different HCV genotypes by crystallographic modeling. Different softwares were used to study the interaction pattern, for example, CLCBIO sequence viewer, MODELLER, NMRCLUST, ERRAT score, and MODELLER. ...

A geometric modeller is a piece of software allowing to create, manipulate and modify geometric objects. Modern geometric modellers usually use a mathematical model to represent objects and are developed around a kernel that proposes basic operations to create and manipulate objects called by high level operations. Because of these proceedings, the context is a priori in favour of the use of fo...

We introduce MASSPA–Modeller, a visual modelling tool for the recently developed spatial stochastic process algebra MASSPA which describes Markovian Agent Models (MAM)s. The major advantage of using a visual editor to generate MASSPA models is that the laborious task of modelling the communication between agents is partially automated by the tool. Furthermore the tool can separately check the c...

Discussions of conceptual modelling assume that notation details are of secondary importance, a matter of taste and past experience rather than of science. For example, it does not really matter if cardinality is shown with a ‘crow’s foot’ or with the symbol ‘1..*’. This paper argues that such an assumption is wrong and that the notation is extremely important in the process of modelling relati...