Endocrine-disrupting compounds are exogenous agents that interfere with the natural hormones of the body. Human biological monitoring is a powerful method for monitoring exposure to endocrine disrupting compounds. In this review, we describe human biological monitoring systems for different groups of endocrine disrupting compounds, polychlorinated biphenyls, brominated flame retardants, phthala...

BACKGROUND Here, we analyzed the dose- (0.2, 2, 20, 200 nM or 2 μM) and time- (48, 96, 144 and 196 h) dependent activity of a single or repeated exposure of methyl-, butyl- and propylparaben on the proliferation of MCF-7 human breast cancer cells and MCF-10A human breast epithelial cells. Additionally, the effect on estradiol secretion, gene and protein expression of aromatase (CYP19A1) was inv...

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Preservatives such as benzoic acid and parabens are being tested on a regular basis by regulatory authorities and food testing laboratories as they are widely found in condiments and beverages such as fruit juices, sports drinks and soft drinks. The consumption of excessive amount of preservatives can lead to adverse health effects such as allergy. Also, the levels of these preservatives in foo...

Very low birth weight infants (VLBW; < 1500 g) are treated with pharmaceuticals and medical equipment containing parabens bisphenol A (BPA). Parabens used in pharmaceuticals, whereas BPA where concentrations rarely reported hospitalised VLBW infants. We measured urinary of hypothesised high increasing born at lower gestational ages (GAs), among bronchopulmonary dysplasia (BPD) late-onset septic...

Two different chelator-based antimicrobial catheter lock solutions, methylene blue-citrate-parabens (MB-CIT) and minocycline-EDTA-25% ethanol (M-EDTA-25% ETOH), were compared in 2-h biofilm eradication experiments. Eradication of both mature and immature Gram-positive, Gram-negative, and fungal biofilms was assessed. M-EDTA-25% ETOH was able to fully eradicate all biofilms within 2 h. MB-CIT wa...