A 45-year-old human immunodeficiency virus (HIV)-positive male from northeastern India presented with fever and cough as well as a 3-month-old ulcer over the chin. On examination, there was a 5 × 5-cm superficial ulcer with a thick adherent crust over the chin ( Figure 1 ). The individual had three papules with central umbilication over the neck and face. He had anemia (hemoglobin = 7.5 g) and ...

Dear Editors, Epidermal growth factor receptor (EGFR) inhibitors such as erlotinib and gefitinib have been established as effective therapies for non-small cell lung cancer, pancreatic cancer, colorectal cancer, and head and neck cancer (1). However, a number of skin manifestations, such as acneiform papules, xerosis, photosensitive dermatitis, pruritus, perionychia and vasculitis have been rep...

A 34-year-old Chinese man had been experiencing asymptomatic, pinpoint-sized, skin-colored, umbilicated papules distributed throughout his left palm for more than 10 years. Physical examination showed multiple, discrete, flesh-colored, flat-topped shiny papules, some of which were like molluscum, dispersed across the (Figure 1A), measuring about 1-2 mm in diameter 1B). The patient's family hist...