Oripavine is the major alkaloid of Papaver orientale. It is an important intermediate in the biosynthesis of morphine alkaloids. Recently, new Papaver somniferum strains have been developed which accumulate thebaine and oripavine, but not morphine and codeine. Therefore, the chemistry of oripavine has been studied intensively to synthesize opioid pharmaceuticals such as oxymorphone, naloxone an...

Introduction. In this paper, we aimed to present five Papaver rhoeas intoxication cases, which is very rare in the literature. Case 1. A 35-year-old female patient was admitted to our emergency room with the complaints of nausea, restlessness, and dyspnea developing 3 hours after eating Papaver rhoeas. On physical examination, her general condition was moderate; she was conscious and the vital ...

asthma is a chronic inflammatory disorder of the airways. the available treatment options have major limitations owing to low efficacy, associated adverse events and compliance issues. therefore, the health burden of bronchial asthma is increasing globally at an alarming rate, providing a strong impetus for the development of new therapeutics. onosma bracteatum ( o. bracteatum ) is known tradit...

Application of exogenic bioactive natural plant compounds with protective, anti-mutagenic and anti-genotoxic effects against various chemical and physical agents is one of the modern approaches for reduction of the mutagenic burden of cells. Objective: The present study aims to provide data on the cytoxic and genotoxic effects of Papaver rhoeas L. water leaf extract and its anti-cytotoxic and a...

The Papaveraceae represent a large family divided into 23 genera with more than 300 species, distributed world-wide in subtropical and temperate regions (Reveal, 1999). The genus Papaver L. is represented by more than 120 species, rich in isoquinoline and morphinane alkaloids (Preininger, 1986). In our previous phytochemical studies on Papaver nudicaule L. growing in Mongolia, we reported the i...