This study aimed at compare influences of airway pressure release ventilation (APRV) and Synchronized Intermittent Mechanical Ventilation (SIMV) on intracranial pressure and oxygenation status in patients with traumatic brain injuries. A clinical trial was carried out in 40 patients with traumatic brain injuries in the intensive care unit in Kamyab neurosurgery Hospital, Mashhad, Iran. The pati...

PURPOSE To assess the effects of systemic hypoxia and hyperoxia on the volume of the subretinal space (SRS). METHODS The authors measured the concentration of the extracellular space marker tetramethylammonium (TMA+) in the intact cat eye using double-barreled ion-selective microelectrodes. The retina was loaded with TMA+ by a single intravitreal injection. Systemic hypoxia was induced by add...

Baum, J. D., and Bulpitt, C. J. (1970). Archives of Disease in Childhood, 45, 350. Retinal vasoconstriction in premature infants with increased arterial oxygen tensions. Retinal vessels of newborn and premature infants were photographed under conditions of increasing arterial oxygen tension and the changes in vessel diameter were measured. In 6 infants studied, there was a consistent pattern of...

To determine whether or not a "bolus injection" of soybean-based fat emulsion (SFE), which contains oleic acid (OA), a potent lung-toxic unsaturated C-18 fatty acid, can induce pulmonary dysfunction, we examined the effect of SFE injection on the partial oxygen pressure of arterial blood (Pao2) and pulmonary vascular permeability. In addition, we compared the effect of an injection of SFE with ...

OBJECTIVE To evaluate gasometric differences of severe trauma patients requiring intubation in prehospital care. METHODS Patients requiring airway management were submitted to collection of arterial blood samples at the beginning of pre-hospital care and at arrival at the Emergency Room. We analyzed: Glasgow Coma Scale, respiratory rate, arterial pH, arterial partial pressure of CO2 (PaCO2), ...

Mục tiêu: Đánh giá bước đầu hiệu quả cải thiện oxy hóa máu của phương pháp thông khí cơ học tư thế nằm sấp ở bệnh nhân suy hô hấp cấp tiến triển tại Trung tâm Hồi sức tích cực, Bệnh viện ương Quân đội 108. Đối tượng và pháp: 18 mức độ trung bình hoặc nặng (PaO2/FiO2 < 150mmHg với PEEP ≥ 5cmH2O, FiO2 60%) điều trị Khoa TWQĐ 108 từ tháng 02/2020 đến 09/2021 được chỉ định sấp. Kết quả: Tỷ lệ có...

Results At baseline the arterial oxygen tension (PaO2) was 539 ± 50 mmHg and 508 ± 35 mmHg in Controls and NaNO2 i.v. respectively (fraction of inspired oxygen = 1.0). PaO2 decreased to 67 ± 17 mmHg (Controls) and 57 ± 13 mmHg (NaNO2 i.v.) after ARDS induction. During the protocol, PaO2 increased to 120 ± 73 mmHg (Controls) and 103 ± 82 mmHg (NaNO2 i.v.). NOex was unchanged in both groups. Lung...

BACKGROUND Recruitment maneuvers are often used in critical care patients with hypoxemic respiratory failure. Although continuous positive airway pressure/pressure support (CPAP/PS) ventilation is a frequently used approach, but whether lung recruitment also improves oxygenation in spontaneously breathing patients has not been investigated yet. The primary objective was to analyze the effect of...

OBJECTIVE To determine prospectively the efficacy of surfactant in acute respiratory distress syndrome. STUDY DESIGN Twenty patients, 1 month to 16 years of age, diagnosed with an acute pulmonary disease with severe hypoxaemia (PaO2/FiO2 < 100) (13 with systemic or pulmonary disease and seven with cardiac disease) were treated with one to six doses of 50-200 mg/kg of porcine surfactant admini...

BACKGROUND The mechanisms by which partial liquid ventilation (PLV) can improve gas exchange in acute lung injury are still unclear. Therefore, we examined the time- and dose-dependency of the improvements in arterial oxygen tension (PaO2) due to PLV in eight pigs with experimental lung injury, in order to discriminate increases due to oxygen dissolved in perfluorocarbon before its intrapulmona...