This study analyses the effects of vagotomy on tumor growth and survival in a murine, pancreatic cancer model in wild-type and TNFα-knockout (-/-) mice.Throughout many operative procedures in the upper gastrointestinal tract the partial or complete transection of the vagus nerve or its local nerve fibers is unavoidable. Thereby its anti-inflammatory effects in residual tumor tissue may get lost...

Jun Suh LEE, Yoo-Seok YOON*, Ho-Seong HAN, Boram Moonhwan KIM, Yeongsoo JO, Jin-Young JANG, Wooil KWON, Hongbeom Mirang Hee Ju SOHN, Chang-Sup LIM. Ann Hepatobiliary Pancreat Surg 2022;26:S59. https://doi.org/10.14701/ahbps.2022S1.OP-1-1

Background Postoperative pancreatic fistula (POPF) remains a significant cause of morbidity in patients undergoing distal pancreatectomy (DP). The use polyethylene glycol (PEG) and recombinant human albumin sealant gel applied to the transected margin DP may reduce POPF rates was assessed. Methods A retrospective single centre cohort study patient at an Australian high volume tertiary instituti...

Despite recent improvements in surgical technique, the morbidity of distal pancreatectomy remains high, with pancreatic fistula being the most significant postoperative complication. A systematic review of randomized controlled trials (RCTs) dealing with surgical techniques in distal pancreatectomy was carried out to summarize up-to-date knowledge on this topic. The Cochrane Central Registry of...

EARLY RETROPANCREATIC DISSECTION DURING PANCREATICO-DUODENECTOMY TECHNICAL NOTES (ABSTRACT): Background: Pancreaticoduodenectomy (PD) is the procedure of choice for malignant tumors of the pancreatic head and periampullary region. During PD, early pancreatic neck division may be inadequate, especially in cases of hepatic artery (HA) anatomic variants, when invasion of the superior mesenteric ar...

INTRODUCTION During the past three decades, the number of renal transplantations for curative therapy of chronic renal insufficiency has more than quadrupled, with pancreatic transplantation being increasingly used as definitive treatment for diabetes mellitus (1–3). As diabetes mellitus frequently contributes to renal failure, combined (synchronous or metachronous) renal and pancreatic transpl...

BACKGROUND After pancreaticoduodenectomy, the Finnish binding pancreaticojejunal anastomosis (FBPJ) seems to reduce the risk for pancreatic fistula (POPF). Our aim was to investigate whether FBPJ is feasible and prevents the risk for POPF even after left pancreatectomy (LP). PATIENTS AND METHODS 47 consecutive patients underwent LP. 27 patients were recruited on the basis of CT and, of these,...