This systematic review is the product of 25 top published journals. The search engines adopted in this study werePubMed, Medline, CINHAL, Cochrane Library, Google Scholar, and Research gate. inclusion criteria were:1.Papers between 2000-2020, 2.Top tier journal articles (High quality), 3. Term Healthy neonates preterm neonates, 4.Neonates undergoing various painful procedures Neonates receive d...

CONTEXT Evidence to guide selection of optimal surgical treatment for patients with painful chronic pancreatitis is limited. Baseline assessment data are limited and thus patients in different centres may be presenting at different stages of their illness. OBJECTIVE This study undertakes a systematic overview of reports of elective surgical intervention in chronic pancreatitis with particular...

BACKGROUND Children with leukemia undergo painful procedures such as lumbar puncture and bone marrow aspiration. To overcome pain, certain units offer total anesthesia; others offer generic support; others offer no preparation at all. Since September, 1997, we have provided leukemic children with art therapy (AT), a nonverbal and creative modality that develops coping skills. Our goal is to pre...

The aims of this study were to identify which aspects of castration are painful to piglets, and to determine if less painful methods are available. Previous work has shown that piglets produce more high frequency calls (>1kHz) when castrated than when handled identically but not castrated, or when castrated using a local anesthetic. In Experiment 1, we used 90 piglets to assess the vocal respon...

This prospective study of comparing transperineal prostate biopsy (TPBx) with transrectal prostate biopsy (TRBx) was aimed to provide evidence for clinicians to select the appropriate biopsy approach under different conditions. TPBx (n = 173) and TRBx (n = 166) were performed randomly for 339 patients who were suspicious of prostate cancer (PCa). The cancer detection rate (CDR), complication ra...

Although it has long been known that psychosocial factors play a crucial role in placebo responses, no attempt has been made to understand if social observation shapes the placebo analgesic effect. To address this question, we compared placebo analgesia induced through social observation (Group 1) with first-hand experience via a typical conditioning procedure (Group 2) and verbal suggestion al...

Aspirations or Jamshidi needle biopsies (n = 287) of bone marrow were performed on children and adolescents with acute leukemia or other malignant disease following the use of a spring-loaded instrument that delivered local anesthetic in a jet spray; 89% of the patients were receiving chemotherapy, 12% were thrombocytopenic, and 23% of the 269 patients who were afebrile at the time of the proce...

The nocebo effect consists in delivering verbal suggestions of negative outcomes so that the subject expects clinical worsening. Here we show that nocebo suggestions, in which expectation of pain increase is induced, are capable of producing both hyperalgesic and allodynic responses. By extending previous findings on the placebo effect, we investigated the role of learning in the nocebo effect ...

A 40-year-old male patient was admitted with complaints of right shoulder pain and decreased range of motion for two days. He was diagnosed with axillary web syndrome. Palpable subcutaneous cord which extended from axillary crease down to the ipsilateral arm was revealed. He was administered a non-steroidal anti-inflammatory drug and arranged 15 sessions of physical therapy. To the best of our ...

The authors describe the first surgical case adopting the combination of real-time augmented reality and wearable computing devices such as Google Glass (Google Inc, Mountain View, California). A 66-year-old man presented to their institution for a total shoulder replacement after 5 years of progressive right shoulder pain and decreased range of motion. Throughout the surgical procedure, Google...