Cannabinoids are the most commonly recognized herbal plant, having much medicinal importance from ancient times and plays an important role in Indian culture. Now a day’s cannabinoids used for many therapeutic purposes, under clinical trial by various institutions. In latest discovery within humans, it was found that we also have cannabinoids, receptors, enzymes our body, so is termed as endoca...

introduction: the formalin test is the most accepted chemical test for evaluation of nociception. it requires the injection of an adequate amount of formalin into the surface of the hindpaw. formalin test consists of phase 1 (0-7 min) and phase 2 (15-60) in which the animal shows painful behaviors. these phases are separated with a quiet phase named interphase, in which the nociceptive response...