Objective To compare post-operative pain relieving effect of topical diclofenac 0.1% versus ketorolac 0.5% in Corneal Collagen Cross Linking (CXL) for patients diagnosed with keratoconus. Methods This randomized controlled trial was carried out for six months from October 2016 to March 2017. We included young patients having keratoconus with k-readings greater than 47D and central corneal thi...

BACKGROUND Knee osteoarthritis is one of the most prevalent chronic disorders. Several pharmacological and non pharmacological approaches are used to treat this disease. Today, the effect of B and E vitamins on rheumatology diseases is being discussed. In this study, the efficacy of B and E vitamins accompanied with diclofenac on pain relief in patients with knee osteoarthritis was investigated...

OBJECTIVES To evaluate the short-term symptomatic efficacy of rofecoxib and diclofenac versus placebo in acute episodes of shoulder pain. DESIGN Randomized controlled trial of 7 days. SETTING Rheumatologists and/or general practitioners totaling 47. PARTICIPANTS Acute shoulder pain. INTERVENTIONS Rofecoxib 50 mg once daily, diclofenac 50 mg three times daily, and placebo. OUTCOME MEAS...

PURPOSE Use of nonopioid analgesics (including nonsteroidal anti-inflammatory drugs) for postoperative pain management can reduce opioid consumption and potentially prevent opioid-related adverse events. This study examined the postoperative opioid-sparing effect of repeated-dose injectable diclofenac formulated with hydroxypropyl-β-cyclodextrin (HPβCD)-diclofenac. PATIENTS AND METHODS Pooled...

Aim: Ibuprofen400mg and Diclofenac Sodium 50mg marketed today inhibit Cox-1 and Cox-2 and have selectivity for Cox-1. Ibuprofen 400mg is an established analgesic in the management of acute dental pain. Diclofenac Sodium 50mg is also used in the management of acute pain, but there are very few studies comparing its analgesic efficacy with Ibuprofen. Materials and Method: A double blind randomize...

OBJECTIVE To compare the ketoprofen TDS patch with diclofenac gel in the treatment of traumatic acute pain in benign sport-related soft-tissue injuries. DESIGN 7-14 treatment days, prospective, randomised, open study. PATIENTS Outpatients aged 18-70 years diagnosed for painful benign sport-related soft-tissue injury (sprains, strains and contusions within the prior 48 h), randomised to eith...

BACKGROUND Tonsillectomy is a common procedure causing considerable postoperative pain. Postoperative pain intensity of 60 - 70 in the scale of visual analog scale (VAS) has been reported up to 3 - 4 days which could continue until 11 days after the surgery. OBJECTIVES The current study aimed to compare the analgesic effect of gabapentin and diclofenac on pain after tonsillectomy with the con...

Diclofenac potassium is a widely used non-steroid anti-inflammatory drug which is absorbed more quickly than diclofenac sodium, Reported cases of rhabdomyolisis after only diclofenac are rare, we survey three cases in the literature. . We report a case of a 50 year-old man, chronic smoker and allergic to aspirin who developed a rhabdomyolysis associated with glossopharyngeal edema after oral ad...

The present study was performed to investigate the effects of long-term intraperitoneal (IP) injection of vitamin B12 and diclofenac in separate and combined treatments on cold and mechanical allodynia in a neuropathic pain model in rats. Neuropathic pain was induced by crush injury in right tibial nerve. Acetone spray and von Frey tests were used to obtain cold and mechanical allodynia respons...

Dear Editor, We have examined attentively the latest manuscript by Yeganeh Mogadam et al. entitled " Comparison of Analgesic Effect between Gabapentin and Diclofenac on Post-Operative Pain in Patients Undergoing Tonsillectomy " available in Archives of Trauma Research (1). Ninety patients were included to receive 20 mg/kg oral gabapentin (n = 30), 1.0 mg/kg rectal diclofenac (n = 30) or placebo...