نتایج جستجو برای: paced visual serial addition test

تعداد نتایج: 1818294  

2015
Michael J. Larson James D. LeCheminant Kyle Hill Kaylie Carbine Travis Masterson Ed Christenson

PURPOSE This study compared cognitive (attention, learning, and memory) and typing outcomes during slow treadmill walking or sitting. Seventy-five healthy individuals were randomly assigned to a treadmill walking group (n=37; 23 female) or sitting group (n=38; 17 female). METHODS The treadmill walking group completed a series of tests while walking at 1.5 mph. The sitting group performed the ...

Journal: :AJNR. American journal of neuroradiology 2013
P K Bhattacharyya M D Phillips L A Stone R A Bermel M J Lowe

BACKGROUND AND PURPOSE Abnormalities in GABA concentration [GABA] have been associated with several neuropsychiatric disorders, and research has suggested that GABA may play a role in sensorimotor cortex function. We sought to determine whether identifying a change in [GABA] within the sensorimotor cortex of patients with MS has any effect on motor function and would provide information about t...

Journal: :Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists 2006
Angela L Jefferson Robert H Paul Al Ozonoff Ronald A Cohen

OBJECTIVE Executive functioning has been repeatedly linked to the integrity of instrumental activities of daily living (IADL). The present study examined the association of multiple executive functioning elements (i.e., working memory, generation, inhibition, planning, and sequencing) to IADLs among an older adult cohort at risk for future cognitive and functional decline. METHODS Seventy-two...

2013
Laura Wieder Gunnar Gäde Luisa M Pech Hanna Zimmermann Klaus-Dieter Wernecke Jan-Markus Dörr Judith Bellmann-Strobl Friedemann Paul Alexander U Brandt

BACKGROUND Cognitive impairment and visual deterioration are two key clinical symptoms in MS and affect 50 to 80% of patients. Little is known about the influence of cognitive impairment on visual tests recommended for MS such as low contrast sensitivity testing. Our objective was to investigate whether low contrast sensitivity testing is influenced by cognitive impairment in multiple sclerosis...

Journal: :Multiple sclerosis and related disorders 2015
Gro O Nygaard Sigrid A de Rodez Benavent Hanne F Harbo Bruno Laeng Piotr Sowa Soheil Damangir Kristian Bernhard Nilsen Lars Etholm Siren Tønnesen Emilia Kerty Liv Drolsum Nils Inge Landrø Elisabeth G Celius

PURPOSE Eye and hand motor dysfunction may be present early in the disease course of relapsing-remitting multiple sclerosis (RRMS), and can affect the results on visual and written cognitive tests. We aimed to test for differences in saccadic initiation time (SI time) between RRMS patients and healthy controls, and whether SI time and hand motor speed interacted with the written version of the ...

2016
Gavin Giovannoni Ralf Gold Ludwig Kappos Douglas L Arnold Amit Bar-Or Jing L Marantz Minhua Yang Andrew Lee

The effect of delayed-release dimethyl fumarate (DMF; also known as gastro-resistant DMF) on the Multiple Sclerosis Functional Composite (MSFC) was assessed using integrated Phase 3 DEFINE and CONFIRM data. Patients treated with DMF (n = 769) demonstrated significant superiority on the MSFC, and each component, compared with placebo (n = 771) over two years: mean change for DMF vs placebo was 0...

2009
W. Van Hecke J. Sijbers A. Leemans G. Nagels E. Vandervliet P. M. Parizel

Introduction: The aim of this study was to examine differences diffusion tensor imaging (DTI) measures between healthy subjects on the one hand and mildly and moderately affected Multiple Sclerosis (MS) patients on the other hand. In addition, the relationship between the Paced Auditory Serial Addition Test (PASAT) tests of cognitive decline and micro-structural white matter breakdown, as asses...

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