Tandemly repeated endogenous genes are common in plants, but their transcriptional regulation is not well characterized. In maize, the P1-wr allele of pericarp color1 is composed of multiple copies arranged in a head-to-tail fashion. P1-wr confers a white kernel pericarp and red cob glume pigment phenotype that is stably inherited over generations. To understand the molecular mechanisms that re...

BACKGROUND AND OBJECTIVE The gene responsible for the P1 polymorphism of the P blood-group system remains unidentified, although the A4GALT gene, whose product is responsible for the production of P(k), has been implicated. No coding differences in A4GALT account for the P1 polymorphism, but homozygosity for two polymorphisms (-551_-550insC and -160A>G) in the 5' untranslated region of the gene...

Plasminogen activator inhibitor-1 (PAI-1) is a specific inhibitor of the serine proteases tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA). To systematically investigate the roles of the reactive center P1 and P1' residues in PAI-1 function, saturation mutagenesis was utilized to construct a library of PAI-1 variants. Examination of 177 unique recombinant p...

The genomes of three Pseudoalteromonas strains (P1-8, P1-11, and P1-30) were sequenced and assembled. These genomes will inform future study of the genes responsible for the production of biologically active compounds responsible for these strains' antimicrobial, biofouling, and algicidal activities.

The lateral ribosomal stalk is responsible for the kingdom-specific binding of translation factors and activation of GTP hydrolysis during protein synthesis. The eukaryotic stalk is composed of three acidic ribosomal proteins P0, P1 and P2. P0 binds two copies of P1/P2 hetero-dimers to form a pentameric P-complex. The structure of the eukaryotic stalk is currently not known. To provide a better...

The terminology and notation used here are introduced in the following articles: [24], [27], [1], [3], [4], [2], [14], [12], [25], [22], [23], [11], [21], [8], [9], [6], [26], [15], [10], [18], [17], [5], [20], [19], [7], [13], and [16]. In this paper n is a natural number. We now state a number of propositions: (1) For all subsets A, B of E T such that A meets B holds proj1◦ A meets proj1◦ B. ...

(7) 2 · (p+q) ∈ L(p,q). (8) If p1 = q1 and q1 = (p1)1 and p2 ≤ q2 and q2 ≤ (p1)2, then q ∈ L(p, p1). (9) If p1 ≤ q1 and q1 ≤ (p1)1 and p2 = q2 and q2 = (p1)2, then q ∈ L(p, p1). (10) Let D be a non empty set, given i, j, and M be a matrix over D. If 1 ≤ i and i ≤ lenM and 1 ≤ j and j ≤ widthM, then 〈i, j〉 ∈ the indices of M. (11) If 1 ≤ i and i + 1 ≤ lenG and 1 ≤ j and j + 1 ≤ widthG, then 2 · ...

Transcription of the LEE1 operon in the locus of enterocyte effacement of enterohaemorrhagic Escherichia coli is due to the P1 promoter. Mutational and biochemical analyses reveal the existence of an overlapping promoter, designated P1A, which can drive transcript initiation 10 bp upstream of the P1 promoter transcript start point. Because of the overlap between P1 and P1A, P1A activity is unma...

A novel light-emitting monomer M1 and its side-chain polymer P1 containing three conjugated aromatic pendants, including one pyridyl terminus, were successfully synthesized via Wittig and Pd-catalyzed Heck coupling reactions. The fluorescence of polymer P1 was efficiently quenched upon addition of different metal ions due to the facile energy transfers from the pendent groups of polymer P1 to s...