Neutral or cationic arene ruthenium complexes providing both hydrophilic as well as hydrophobic properties due to the robustness of the ruthenium-arene unit hold a high potential for the development of metal-based anticancer drugs. Mononuclear arene ruthenium complexes containing P- or N-donor ligands or N,N-, N,O- or O,O-chelating ligands, dinuclear arene ruthenium systems with adjustable orga...

The synthesis and NOE-based structural characterization is described of thiacalix[4]arene tricarboxylic acid (7), thiacalix[4]crown-5 and -6 monocarboxylic acids (2 and 5), and the bis(N-methylsulfonyl)thiacalix[4]crowns-5 and -6 (4a,b). The 226Ra2+ selectivity coefficients, log(K(Ra)ex/K(M)ex), of the new thiacalix[4]arene derivatives are compared directly with those of thiacalix[4]crown-5 and...

A new water-soluble thermoresponsive pillar[6]arene with triethylene oxide groups was synthesized. The pillar[6]arene showed lower critical solution temperature behavior in aqueous solution. Its clouding point was photoreversibly switched based on a photoresponsive host-guest system. The trans form of an azobenzene guest formed a stable 1:1 complex with the pillar[6]arene. Complexation increase...

A series of calix[4]arene-supported Ln(III)(6) clusters have been synthesised under facile bench top conditions. The magnetic and structural properties of these clusters are reported, the latter suggesting that the Ln(III)-calix[4]arene moiety may be used for the construction of other assemblies in a manner akin to that for the Mn(III)-calix[4]arene analogue.

Three large negatively charged organic host molecules; β-cyclodextrin sulphate, para-sulphonato-calix[6]arene and para-sulphonato-calix[8]arene have been shown to be effective inhibitors of endonuclease in the low micromolar range, additionally para-sulphonato-calix[8]arene is a partial inhibitor of rhDNase I.

In this study, we examine macrocyclic compounds to determine whether they can provide a safer replacement and stable complex for BPA in thermochromic dyes. To achieve objective, series of compounds, Methyl-N-benzylhexahomotriazacalix[3]arene (MeAC3), p-Chloro-N-benzylhexahomo-triazacalix[3]arene (ClAC3), ?-Cyclodexdrin (?-CD), ?-Cyclodexdrin (?-CD), p-tert-Butylthiacalix[4]arene (TC4), Calix[4]...

Reactions of 0.5 eq. of the dinuclear complexes [(g-arene)Ru(l-Cl)Cl]2 (arene = g-C6H6, g-p-PrC6H4Me) and [(Cp*)M(l-Cl)Cl]2 (M = Rh, Ir; Cp* = g-C5Me5) with 4,6-disubstituted pyrazolyl-pyrimidine ligands (L) viz. 4,6-bis(pyrazolyl)pyrimidine (L1), 4,6-bis(3-methyl-pyrazolyl)pyrimidine (L2), 4,6-bis(3,5dimethyl-pyrazolyl)pyrimidine (L3) lead to the formation of the cationic mononuclear complexes...

Non-covalent inclusion complexes formed between amino acids and derivatized calix[6]arenes are observed in MALDI mass spectrometry. The methyl, ethyl, and propyl ester derivatives of calix[6]arene yielded amino acid complexes, while the smaller calix[4]arene analogs did not. Similarly the underivatized calix[6]arene and calix[4]arene did not produce complexes. Amino acid complexes were observed...

The dinuclear dichloro complexes [(g-arene)2Ru2(l-Cl)2Cl2] and [(g-C5Me5)2M2(l-Cl)2Cl2] react with 2-(pyridine-2-yl)thiazole (pyTz) to afford the cationic complexes [(g-arene)Ru(pyTz)Cl] (arene = C6H6 1, p-PrC6H4Me 2 or C6Me6 3) and [(g-C5Me5)M(pyTz)Cl] (M = Rh 4 or Ir 5), isolated as the chloride salts. The reaction of 2 and 3with SnCl2 leads to the dinuclear heterometallic trichlorostannyl de...