The role of leptin in controlling food intake and body weight is well recognized, but whether this is achieved by modulating nutrient absorption is still a controversial issue. The aim of this work was to investigate the direct effect of luminal leptin on glucose intestinal absorption and elucidate for the first time its signaling pathway. Fully differentiated Caco-2 cells grown on transwell fi...

Changes in the absorption spectra o f P. cruentum and phycobiliprotein are observed as a function o f hydrostatic pressure. With phycobiliprotein both in solution and in algae, increasing hydrostatic pressure results in bathochromic shifts o f the absorption maxima. In addition, there is a splitting o f the absorption band of phycoerythrin. When P. cruentum is subjected to 250 bars there are in...

Four pigs initially of 30 kg live weight were surgically prepared with two re-entrant cannulas in the jejunum 1.0 m apart which allowed an isolated loop to be formed through which solutions were perfused. 51Cr-EDTA was used as a marker for measuring net secretion or absorption. A new Ringer solution was made, the ionic content of which resembled more closely that found in the jejunum of pigs gi...

BACKGROUND Low iron absorption from important staple foods may contribute to iron deficiency in developing countries. To date, few studies have examined the iron bioavailability of pulse crops as commonly prepared and consumed by humans. OBJECTIVE The objectives were to characterize the iron absorption from a test meal of intrinsically labeled (57)Fe lentils prepared as dal, to compare the bi...

Subjects with increased cholesterol absorption might benefit more from statin therapy combined with a cholesterol absorption inhibitor. We assessed whether baseline cholesterol absorption markers were associated with response to ezetimibe/simvastatin therapy, in terms of LDL-cholesterol (LDL-C) lowering and cholesterol absorption inhibition, in patients with familial hypercholesterolemia (FH). ...

The percutaneous absorption of hydrocortisone and testosterone was studied following their application to the vulvar and ventral forearm regions of pre- and post-menopausal women. Percutaneous absorption of hydrocortisone was significantly greater in vulvar skin than forearm skin in both pre- and post-menopausal women (P < 0.05, respectively), whereas the percutaneous absorption of testosterone...

We present a short review of the current quasar (QSO) absorption line constraints on possible variation of the fine structure constant, α ≡ e 2 /¯ hc. Particular attention is paid to recent optical Keck/HIRES spectra of 49 absorption systems which indicate a smaller α in the past [1, 2]. Here we present new preliminary results from 128 absorption systems: ∆α/α = (−0.57 ± 0.10) × 10 −5 over the ...

BACKGROUND Considerable data are available on the individual effects of dietary factors on nonheme-iron absorption, but their combined effect when they are present in the same meal is not known. OBJECTIVE Our objective was to predict the bioavailability of iron from complex meals that are consumed commonly in the United States on the basis of the contents of factors that are known to promote ...

Percent cholesterol absorption was measured in 94 normal subjects aged 17- 80 years while consuming diets generally low in cholesterol (mean intake = 226 +/- 126 mg/day). A new dual stable isotope method was used where a cholesterol tracer containing 6 extra mass units was given intravenously and another tracer with 5 extra mass units was given orally during a standard test meal. The ratio of t...