Oxygen use in prehospital care is aimed at treating or preventing hypoxemia. However, excess oxygen delivery has important consequences in select patients, and hyperoxia can adversely impact outcome. The unique environment of prehospital care poses logistical and educational challenges. Oxygen therapy in prehospital care should be provided to patients with hypoxemia and titrated to achieve norm...

Cockcroft S. Monomeric IgE stimulates NFAT translocation into the nucleus, a rise in cytosol Ca2+, degranulation, and membrane ruffling in the cultured rat basophilic leukemia-2H3 mast cell line. J Immunol 2004; 172: 4048–4058. 5 Nunomura S, Gon Y, Yoshimaru T, et al. Role of the Fc (varepsilon) RI (b)-chain ITAM as a signal regulator for mast cell activation with monomeric IgE. Int Immunol 200...

The article by Sharifipour et al, covers an extremely important area of unmet medical need in ophthalmology. 1 Severe ischemia of the sclera, leading to necrotizing disease and possible scleral melt, is one of the veritable emergencies among anterior segment disorders. Causes of necrotizing scleral disease are myriad and include autoimmune disease, especially vasculitides (e.g. Wegener's granul...

ong-term oxygen therapy (LTOT) is an important adjunct in the treatment of many hypoxemic patients. Appropriate prescription by the physician requires knowledge ofthe rationale for oxygen therapy, the indications for its use, and the appropriate delivery system for individual patients. Recommendations for use of LTOT should be guided by clear data, clinical judgment, and the consensus recommend...

a significant reduction in arterial blood oxygen saturation during fiberoptic bronchoscopy has been proved but it is not yet known whether all patients need supplemental oxygen during this procedure. the aim of study is to examine the relationship between peak expiratory flow rate (pefr) before bronchoscopy and oxygen desaturation during bronchoscopy. measurement of pefr (% predicted) performed...

The author describes the history of and potential medical uses for hyperbaric oxygen (HBO) therapy, a useful adjunct to more established therapies.

Oxygen therapy is defined as the therapeutic use of oxygen and consists of administering oxygen at higher concentrations than those found in room air, with the aim of treating or preventing hypoxia. This therapeutic intervention has been shown to increase survival in patients with chronic obstructive pulmonary disease (COPD) and respiratory failure. Although this concept has been extended by an...

Oxygen therapy is one of the most critical consideration in the management of diseases crossing different medical and surgical specialities. But this is one subject which remains poorly understood and inadequately practiced. Invariably, enormous errors are committed in the use of oxygen.1-3 Oxygen prescription often comprises of a single written word — oxygen. Frequently, it is administered mer...