More accurate methods for monitoring cerebral blood flow, oxygen, and glucose metabolism with results of their application in human volunteers are described. Subjects with various types of cerebral vascular disease showed decreased cerebral blood flow and oxygen and glucose metabolism but anaerobic glycolysis appeared to be increased. Inhalation of 100% oxygen decreased anaerobic glycolysis, an...

More accurate methods for monitoring cerebral blood flow, oxygen, and glucose metabolism with results of their application in human volunteers are described. Subjects with various types of cerebral vascular disease showed decreased cerebral blood flow and oxygen and glucose metabolism but anaerobic glycolysis appeared to be increased. Inhalation of 100% oxygen decreased anaerobic glycolysis, an...

Inhaled anticholinergics may be the first-line therapy for stable COPD. However, the effect of inhaled anticholinergic agents on exercise capacity is still controversial. Fourteen patients with stable COPD (age, 64.6 +/- 5.9 years) completed a randomized, double-blind placebo-controlled crossover trial. All the patients were studied by symptom-limited progressive cycle ergometry before and 90 m...

BACKGROUND Home oxygen therapy is a mainstay of treatment for patients with various cardiopulmonary diseases. In spite of warnings against smoking while using home oxygen, many patients sustain burn injuries. OBJECTIVES We aimed to quantify the morbidity and mortality of such patients admitted to our regional burn unit over a 6-year period. METHODS A retrospective chart review of all patien...

Fifty one infants who were oxygen dependent after treatment for neonatal respiratory disease were entered into a study programme where 100% oxygen was delivered at low flow through a nasal catheter. Thirty five (69%) of the infants were discharged home and the remainder were either discharged to a convalescent hospital or back to their peripheral referring hospital. Excluding repeat admissions ...

Hyperbaric oxygen therapy (HBOT) has been proved as an important tool in healing of CO poisoning, necrosis, ischemic wounds, inflammatory diseases or brain injuries. Reactive oxygen species (ROS) play a key role in healing potential of HBOT however potential side effects must be taken into account. Equally important is also duration of HBOT. We can conclude, that despite several decades of HBOT...

Inhaled nitric oxide (NO) is occasionally used to treat hypoxemia for patients with acute respiratory distress syndrome (ARDS) in the intensive care unit (ICU). However, it is controversial whether or not to maintain inhalation of NO during general anesthesia because of complications, such as nitrogen dioxide (NO(2)) production, methemoglobinemia, and inhibition of platelet aggregation. In this...

BACKGROUND Germinal matrix hemorrhage (GMH) is a neurological disease of very low birth weight premature infants leading to post-hemorrhagic hydrocephalus, cerebral palsy, and mental retardation. Hydrogen (H2) is a potent antioxidant shown to selectively reverse cytotoxic oxygen-radical injury in the brain. This study investigated the therapeutic effect of hydrogen gas after neonatal GMH injury...

Context Periodontal surgical procedures produce varying degree of stress in all patients. Nitrous oxide-oxygen inhalation sedation is very effective for adult patients with mild-to-moderate anxiety due to dental procedures and needle phobia. Aim The present study was designed to perform periodontal surgical procedures under nitrous oxide-oxygen inhalation sedation and assess whether this tech...