نتایج جستجو برای: oxygen carrier

تعداد نتایج: 278738  

Journal: :Anesthesiology 2007
Mark W Crawford Tal Shichor Thomas Engelhardt Gord Adamson David Bell F J Lou Carmichael Peter C W Kim

BACKGROUND Erythrocyte transfusion decreases morbidity in sickle cell disease, but is not without risk. Use of a hemoglobin-based oxygen carrier could offer the benefits of erythrocyte transfusion while reducing related complications. The authors tested the hypothesis that the novel hemoglobin-based oxygen carrier, HRC 101, would improve survival during exposure to acute hypoxia in a murine mod...

2012
James J. Kwan Mehmet Kaya Mark A. Borden Paul A. Dayton

Means to overcome tumor hypoxia have been the subject of clinical investigations since the 1960's; however these studies have yet to find a treatment which is widely accepted. It has been known for nearly a century that hypoxic cells are more resistant to radiotherapy than aerobic cells, and tumor hypoxia is a major factor leading to the resistance of tumors to radiation treatment as well as se...

Journal: :Catalysts 2022

The Cu-based oxygen carrier is a promising material in the chemical looping with uncoupling (CLOU) process, while its performance CLOU significantly dependent on release properties. However, study of mechanisms not comprehensive enough. In this work, detailed CuO(110) and CuO(111) are researched at an atomic level using density functional theory (DFT) method, including formation O2, desorption ...

Journal: :Critical care medicine 2011
David K Shellington Lina Du Xianren Wu Jennifer Exo Vincent Vagni Li Ma Keri Janesko-Feldman Robert S B Clark Hülya Bayir C Edward Dixon Larry W Jenkins Carleton J C Hsia Patrick M Kochanek

OBJECTIVE Resuscitation of hemorrhagic hypotension after traumatic brain injury is challenging. A hemoglobin-based oxygen carrier may offer advantages. The novel therapeutic hemoglobin-based oxygen carrier, polynitroxylated pegylated hemoglobin (PNPH), may represent a neuroprotective hemoglobin-based oxygen carrier for traumatic brain injury resuscitation. HYPOTHESES 1) PNPH is a unique non-n...

2002
J. Powell J. P. O’Neil Joseph Cerny

Lawrence Berkeley National Laboratory, Berkeley, CA 94720, U.S.A. BEARS is an ongoing project to provide a light-ion radioactive-beam capability at the 88-Inch Cyclotron at LBNL. Light radioactive isotopes are produced at a 10 MeV proton medical cyclotron, transported 350 m via a high-speed gas transport capillary, cryogenically separated, and injected into the 88-Inch Cyclotron’s ion source. T...

Journal: :molecular biology research communications 2014
mohammad reza dayer mohammad saaid dayer ali akbar moosavi-movahedi

hemoglobin is a porphyrin containing protein with an a2b2 tetrameric structure and like other porphyrin compounds shows spectral behavior of species specific characteristics. researchers tend to relate bands in the hemoglobin spectra to certain structural and/or functional features. given the fact that hemoglobin is the main oxygen carrier in animals functioning through the oxy«deoxy equilibriu...

Journal: :Anesthesiology 2002
Jan F A Hendrickx José Coddens Frederik Callebaut Hermes Artico Thierry Deloof Ignace Demeyer Andre M De Wolf

BACKGROUND Uptake of a second gas of a delivered gas mixture decreases the amount of carrier gas and potent inhaled anesthetic leaving the circle system through the pop-off valve. The authors hypothesized that the vaporizer settings required to maintain constant end-expired sevoflurane concentration (Etsevo) during minimal-flow anesthesia (MFA, fresh gas flow of 0.5 l/min) or low-flow anesthesi...

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