Al2 (SO4)3, 18H2O, FeCl3 and Ca (OH)2 were used for the treatment of tannery wastewaters. The influences of pH and coagulant dosages were studied. Conditions were optimised according to the pollutant removal efficiencies, the volume of decanted sludge and the biodegradability index improvement. The results indicate that 6771% of total COD, 76-92% of color and 79-97% of Cr can be removed using t...

The infectious diseases caused by antimicrobials pathogens are difficult, harmful, and sometimes impossible to treat. Therefore, design new drugs treat antimicrobial infections is the biggest challenge for modern medicine. 2-Thioxo-4-imidazolidinone used synthesis of a wide variety substituted imidazolidinone derivatives. In this study, we designing eight novel compounds derived 2-thioxo-4-imid...

Measurement of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxo-dG) has recently become more popular as a means of assessing oxidative stress in the human body. Although using high-performance liquid chromatography with electrochemical detection (HPLC-ECD) is a reliable method of measuring 8-oxo-dG, easier and simpler alternative methods may be preferred, if they are quantitatively accurate. ...

We recently identified a novel pathway for the metabolism of 5(S)-hydroxy-6,8,11,14-eicosatetraenoic acid (5-HETE) by human neutrophils, resulting in oxidation of the 5-hydroxyl group to give 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) (Powell, W. S., Gravelle, F., and Gravel, S. (1992) J. Biol. Chem. 267, 19233-19241). This pathway is quite specific for 5-HETE and other eicosanoids conta...

Biodegradability describes the capacity of substances to be mineralized by free-living bacteria. It is a crucial property in estimating a compound's long-term impact on the environment. The ability to reliably predict biodegradability would reduce the need for laborious experimental testing. However, this endpoint is difficult to model due to unavailability or inconsistency of experimental data...

In this paper, we apply various data mining techniques including continuous numeric and discrete classification prediction models of base oils biodegradability, with emphasis on improving prediction accuracy. The results show that highly biodegradable oils can be better predicted through numeric models. In contrast, classification models did not uncover a similar dichotomy. With the exception o...

Sulfur K-edge X-ray absorption spectroscopy (XAS) and density functional theory (DFT) calculations have been used to determine the electronic structures of two complexes [Mo(IV)O(bdt)2](2-) and [Mo(VI)O2(bdt)2](2-) (bdt = benzene-1,2-dithiolate(2-)) that relate to the reduced and oxidized forms of sulfite oxidase (SO). These are compared with those of previously studied dimethyl sulfoxide reduc...

All-trans-retinoic acid (at-RA) induces cell differentiation in a wide variety of cell types, including F9 embryonic teratocarcinoma cells, and can influence axial pattern formation during embryonic development. We now identify a novel retinoid synthetic pathway in differentiating F9 cells that results in the intracellular production of 4-oxoretinol (4-oxo-ROL) from retinol (vitamin A). Approxi...

Mononuclear nonheme iron enzymes generate high-valent iron(IV)-oxo intermediates that effect metabolically important oxidative transformations in the catalytic cycle of dioxygen activation. In 2003, researchers first spectroscopically characterized a mononuclear nonheme iron(IV)-oxo intermediate in the reaction of taurine: α-ketogultarate dioxygenase (TauD). This nonheme iron enzyme with an iro...