The green microalgae Chlorella vulgaris is a source of valuable nutrients, whose bioaccessibility limited by the structurally complex cell wall. Enzymatic degradation wall represents remarkable alternative to mechanical treatments due its mildness and specificity. This work aimed define an optimal combination enzymes increase lipid protein bioaccessibilities C. cells while preserving oxidative ...

Several works suggest that oxidative DNA damage and alterations of DNA repair enzymes in neuronal cells contribute to the onset of neurodegenerative diseases and neuronal cancer. Cadmium is a common environmental pollutant able to induce oxidative stress leading to the activation of neuronal death pathways and it is also able to inhibit specific DNA repair enzymes of the BER (Base Excision Repa...

objective(s) the aim of this study was to evaluate the effects of regular exercise in preventing diabetes complication in the hippocampus of streptozotocin (stz)-induced diabetic rat. materials and methods a total of 48 male wistar rats were divided into four groups (control, control exercise, diabetic and diabetic exercise). diabetes was induced by injection of single dose of stz. exercise was...

Methods are presented for the intramitochondrial localization of various diphosphopyridine nucleotide and triphosphopyridine nucleotide-linked dehydrogenases in tissue sections. The cytochemical reactions studied involve the oxidation of the substrates by a specific pyridino-protein. The electron transfer of tetrazolium salt is mediated by the diaphorase system associated with the dehydrogenase...

Oxidative enzymes catalyze many different reactions in plant metabolism. Among this suite of enzymes are the 2-oxoglutarate/Fe(II)-dependent dioxygenases (2-ODDs). Cytochromes P450 (CYPs) as often considered the most versatile oxidative enzymes in nature, but the diversity and complexity of reactions catalyzed by 2-ODDs is superior to the CYPs. The list of oxidative reactions catalyzed by 2-ODD...

This study evaluated the effect of diesel petroleum intoxication in rats and the ability of phytochemicals and antioxidant content of Ocimum gratissimum to ameliorate such toxicity. Toxicity in rat was induced by administering 4 ml/kg body weight of diesel in the test rats except control. The intoxication and treatment with 20 % O. gratissimum supplemented diet was for 7 days. Serum liver funct...

Many studies reported that redox enzymes, particularly thioredoxin and peroxiredoxin, can be released by cells act as soluble mediators in immunity. Recently, it became clear peroxiredoxins secreted via the exosome-release route, yet remains unclear how this exactly happens why. This review will first introduce briefly possible states of protein cysteines role enzymes their regulation. We then ...

Objectives Oxidative stress induces chronic inflammatory diseases in aerobic organisms, and antioxidants from plants represent an efficient strategy to prevent this condition. Morin hydrate (MH), a bioactive flavonoid, has wide range of pharmacological properties, including anti-inflammatory anti-oxidant. This study evaluated the protective effects MH on lipoteichoic acid (LTA)-induced inflamma...

OBJECTIVE The objective of the present study was to investigate the effect of cadmium (Cd) on the activities of some oxidative enzymes [viz Aldehyde oxidase, AO (E.C. 1.2.3.1); Xanthine oxidase, XO (E.C. 1.2.3.2); Sulphite oxidase, SO (E.C.1.8.3.1.); and Monoamine oxidase, MO (E.C. 1.4.3.4)] in the liver and kidney. MATERIALS AND METHODS Male Wistar albino rats were administered 1, 2 and 4 mg...

Oxidative stress has been known to be involved in pathogenesis of dry eye disease. However, few studies have comprehensively investigated the relationship between hyperosmolarity and oxidative damage in human ocular surface. This study was to explore whether and how hyperosmolarity induces oxidative stress markers in primary human corneal epithelial cells (HCECs). Primary HCECs were established...