Endothelin-2 (EDN2), a potent vasoconstrictive peptide, is transiently produced by periovulatory follicles at the time of ovulation when corpus luteum (CL) formation begins. EDN2 induces contraction of ovarian smooth muscles ex vivo via an endothelin receptor A-mediated pathway. In this study, we aimed to determine if EDN2 is required for normal ovulation and subsequent CL formation in?vivo. In...

Proper coordination of oogenesis, ovulation, and fertilization is essential for successful reproduction. In Caenorhabditis elegans, a strong loss-of-function mutation in dpl-1, which encodes a subunit of the E2F heterodimeric transcription factor EFL-1/DPL-1, causes severe defects during ovulation and fertilization. Here we demonstrate that the somatic gonad structure and sheath cell contractio...

BACKGROUND Ovarian epithelial dysplasia was first described after prophylactic oophorectomies for genetic risk. Ovarian stimulation has been considered as a risk factor of ovarian cancer by Fathalla's incessant ovulation theory. In this study, we have investigated the risk of ovarian dysplasia after ovulation induction. METHODS We reviewed 99 oophorectomies or cystectomies between 1990 and 20...

BACKGROUND Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in females of reproductive age. Insulin resistance is a frequent metabolic disturbance in PCOS. Vitamin D deficiency is a common problem. Accumulating evidence suggests that vitamin D has a role on insulin sensitivity so may contribute to reduction of hyperandrogenemia. OBJECTIVE The aim was to determine the eff...

This study investigated the effect of GnRH analogues on inducing ovulation of dominant follicle (DF)and subsequent corpus luteum (CL) lifespan in the presence of norgestomet implant in Holstein heifers. Onday 6 to 8 of the estrous cycle (day 0 of the experiment), all heifers (n=15) received norgestomet implantfollowed by prostaglandin injection on days 0 and 1. On day 4, group 1 (n=4) and 2 (n=...

How oocytes are transferred into an oviduct with a receptive environment remains poorly known. We found that glands of the Drosophila female reproductive tract, spermathecae and/or parovaria, are required for ovulation and to promote sperm storage. Reducing total secretory cell number by interferring with Notch signaling during development blocked ovulation. Knocking down expression after adult...

The ability to identify the precise time of ovulation is important for women who want to plan conception or practice contraception. Here, we review the current literature on various methods for detecting ovulation including a review of point-of-care device technology. We incorporate an examination of methods to detect ovulation that have been developed and practiced for decades and analyze the ...

Abstract This study assessed the effects of social dominance on behavioral estrus and ovarian parameters dairy goats subjected to synchronous induction during non-breeding season. Synchronous was induced in 23 allocated collective pens. Ovarian ultrasonography performed at 12 h intervals from device removal ovulation. Upon onset (EO) detection, were immediately removed Dominance scored accordin...

Because dates of coitus, ovulation, and fertilization are usually unknown, examination of the duration of gestation in a large series of women is necessarily based on the period of amenorrhoea from onset of menstruation to birth. The considerable variation in this period is due partly to variation in the interval between onset of menstruation and ovulation, and partly to variation in the time b...

Background The pattern of Islamic fasting differs from other forms of fasting, therefore its effect on health also differs. This research studies the effect of Islamic fasting on gonadotropin hormones around the time of the ovulatory cycle and ovulation. MaterialsAndMethods This self-controlled study was performed on 24 adult females. Blood sampling was performed during Ramadan and two months l...