how best to achieve the translation of research evidence into routine policy and practice remains an enduring challenge in health systems across the world. the complexities associated with changing behaviour at an individual, team, organizational and system level have led many academics to conclude that tailored, multifaceted strategies provide the most effective approach to knowledge translati...

The proliferation of systematic reviews and escalating demand from policy makers has driven a newer form of evidence synthesis-overviews of systematic reviews. Systematic Reviews are publishing a special thematic series on overviews and are encouraging submissions on the development and evaluation of methods for this review type. The authors' of this editorial introduce the series by considerin...

BACKGROUND Failure to successfully implement and sustain change over the long term continues to be a major problem in health and social care. Translating evidence into routine clinical practice is notoriously complex, and it is recognised that to implement new evidence-based interventions and sustain them over time, professional behaviour needs to change accordingly. A number of theories and fr...

BACKGROUND Recently, we have published an overview of systematic reviews in allergy epidemiology and identified asthma as the most commonly reviewed allergic disease. Building on this work, we aimed to investigate the quality of systematic reviews in asthma using the AMSTAR checklist and to provide a reference for future, more in-depth assessment of the extent of previous knowledge. METHODS W...

OBJECTIVES To describe the use of systematic reviews or overviews (systematic reviews of systematic reviews) to synthesize quantitative evidence of intervention effects across multiple indications (multiple-indication reviews) and to highlight issues pertaining to such reviews. STUDY DESIGN AND SETTING MEDLINE was searched from 2003 to January 2014. We selected multiple-indication reviews of ...

Introduction Aromatherapy is the field of herbal medicine that uses essential oils distilled from flowers, roots, and herbs other plant compounds to promote physical psychological well-being. Essential are absorbed into body in different ways, with inhaled topical routes being most widely used. The aim this review was critically evaluate synthesize available scientific evidence on efficacy safe...

INTRODUCTION Obstructive sleep apnoea (OSA) is associated with both pulmonary and extrapulmonary consequences. Continuous positive airway pressure (CPAP) is an effective treatment for pulmonary symptoms. However, it is not clear if CPAP modifies extrapulmonary symptoms, especially in the long term. To date, several studies addressing this issue have been performed, but the evidence is scattered...