Using a perfused innervated rat heart model, we studied the sex difference in the sympathetic nerve stimulation-induced norepinephrine release and its presynaptic alpha 2-adrenergic inhibition in normoxic and ischemic conditions. During normoxic perfusion, the alpha 2-adrenoceptor antagonist rauwolscine resulted in a higher overflow of norepinephrine during nerve stimulation in females than in ...

A soft sensor approach is described for controlling metabolic overflow from mixed-acid fermentation and glucose overflow metabolism in a fed-batch cultivation for production of recombinant green fluorescence protein (GFP) in Escherichia coli. The hardware part of the sensor consisted of a near-infrared in situ probe that monitored the E. coli biomass and an HPLC analyzer equipped with a filtrat...

We propose estimators of the buffer overflow probability in queues fed by a Markov-modulated input process and serviced by an autocorrelated service process. These estimators are based on large-deviations asymptotics for the overflow probability. We demonstrate that the proposed estimators are less likely to underestimate the overflow probability than the estimator obtained by certainty equival...

Buffer overflow is a serious problem when the software is run as a server on the internet. Especially when the return addresses are overwritten intentionally, the control flow may be changed as the attacker intends. Although there have been proposed several ways to protect attacks that utilize the buffer overflow, the number of the errors owing to the buffer overflow have been increasing gradua...

Buffer overflow has become a major source of network security vulnerability. Traditional schemes for detecting buffer overflow attacks usually terminate the attacked service, degrading the service availability. In this paper, we propose a lightweight buffer overflow protection mechanism that allows continued network service. The proposed mechanism allows a service program to reconfigure itself ...

When CCD image sensor is exposed to very intense light , an excess charge is generated in photodiode. This excess charge may leak into neighboring cells. This phenomenon is called Blooming. To stop blooming phenomenon an Overflow Drain structure is adapted to suppress this excess charge. In this paper CCD Image sensor with a Vertical Overflow Drain (VOD) structure is investigated in one and two...

Increasingly, software developers are using a wide array of social collaborative platforms for software development and learning. In this work, we examined the similarities in developer’s interests within and across GitHub and Stack Overflow. Our study finds that developers share common interests in GitHub and Stack Overflow; on average, 39% of the GitHub repositories and Stack Overflow questio...

this study investigates the amount of suspended solid particles in three drinking water wells, conducted several times per day in the city of mashhad. the results have also been used for the review and optimization of tested hydro-cyclones. for this purpose, 18 different hydro-cyclones, based on the experimental design process of the taguchi method, were designed and the affecting factors were ...

It is known that moxonidine acts as an agonist at presynaptic alpha(2)-adrenoceptors of the postganglionic sympathetic nerve terminals and leads to a reduction in noradrenaline release. In addition, it is conceivable that I(1)-binding sites located in other regions of the pre- and postganglionic sympathetic neurons are involved in this effect. Our aim was to investigate whether and to what exte...

Bupropion, an efficacious antidepressant and smoking cessation agent, inhibits dopamine and norepinephrine transporters (DAT and NET, respectively). Recently, bupropion has been reported to noncompetitively inhibit alpha3beta2, alpha3beta4, and alpha4beta2 nicotinic acetylcholine receptors (nAChRs) expressed in Xenopus oocytes or established cell lines. The present study evaluated bupropion-ind...