Oncolytic viral therapy is under evaluation for toxicity and efficacy in clinical trials relating to several different tumors. We report a significant increase in the angiogenic index of oncolytic virus (OV)-treated glioma-matrigel implants (2.83-fold, P < 0.02). In a rat intracranial glioma model, large tumors from OV-treated animals were significantly more angiogenic than the phosphate-buffer...

To increase public health awareness for prevention of opisthorchiasis caused by eating raw freshwater fish, the distribution and abundance of Opisthorchis viverrini metacercariae (OV MC) was investigated in freshwater fish obtained from 20 provinces in northeastern Thailand between April 2011 and February 2012. A cross-sectional survey was conducted on 12,890 fish consisting of 13 species rando...

Background—The aim of this study was to validate exhaled nitric oxide (eNO) values obtained with an alternative oV line, single breath, low flow balloon sampling method against on line sampling according to ERS and ATS guidelines in children who could perform both methods. Methods—One hundred and twenty seven white children of median age 14.1 years, all pupils of a secondary school, participate...

Much of the literature on victimization looks at effect organized violence (OV) civilian perceptions and behaviour. Yet citizens in countries experience quotidian crime (QC) a daily basis. QC differs from OV, former being more isolated, while latter is collective experience. As such we develop theoretical framework that explores effects both types preferences for public goods. Victims OV may pr...

BACKGROUND: Ov-CHI-1 is a chitinase specifically expressed in the infective stage larvae of the human filarial parasite Onchocerca volvulus. Evidence has show that it could be a vaccine candidate, however, there is no data available regarding the immunological status of people naturally exposed to infective stage larvae and thus provoked by this antigen. METHOD: We analysed the Ov-CHI-1-specifi...

Photoelectrochemical (PEC) water splitting is a promising approach for renewable solar light conversion. However, surface Fermi level pinning (FLP), caused by trap states, severely restricts the PEC activities. Theoretical calculations indicate subsurface oxygen vacancy (sub-Ov) could release FLP and retain active structure. A series of metal oxide semiconductors with sub-Ov were prepared throu...

Background: Insulin resistance (IR) is frequently associated with hepatitis C virus (HCV) infection, and development of IR can occur early in the course of HCV infection and promote hepatic fibrosis. Aim of the Study: We aimed to assess the impact of IR on the development of oesophageal varices (OV) in HCV-related liver cirrhosis. Subjects and Methods: We enrolled 80 HCV-related liver cirrhosis...

Glyoxal, methylglyoxal and other physiological alpha-oxoaldehydes are formed by the lipid peroxidation, glycation and degradation of glycolytic intermediates. They are detoxified enzymically by the glyoxalase system. To investigate the physiological function of glyoxalase I in parasitic organisms, the cDNA for glyoxalase I from the filarial nematode Onchocerca volvulus (designated Ov-GloI) has ...