Otosclerosis, which is characterized by disordered bone remodeling, occurs exclusively in the human temporal bone. The etiology of the disease is unknown, but a popular hypothesis is that it is caused by persistent measles virus (MV) infection. Paramyxovirus-like filamentous structures were found in otosclerotic lesions of stapes footplates from patients with otosclerosis. Although MV RNAs have...

The efficacy of etidronate, a bisphosphonate, was assessed as a treatment for the inner ear symptoms of otosclerosis in a retrospective case review of 896 patients diagnosed with otosclerosis, with primary complaints of dizziness, hearing loss, tinnitus or Meniere's syndrome. The diagnosis of otosclerosis was based on smallpixel computed tomography of the temporal bones. Of the 896 patients pla...

INTRODUCTION Otosclerosis is an osteodystrophy of the labyrinthine capsule producing conductive hearing loss. If the process invades the cochlea, a sensorineural hearing loss usually takes place. The cochlear implant is a good alternative in these patients. OBJECTIVE To ascertain the behaviour of cochlear implantation in otosclerosis. MATERIAL AND METHODS We reviewed a database of 250 patie...

LASER in the otology field was used to perform tympanotomy and for the placement of ventilation tubes, vaporization of horny pearls and adhesion in the eardrum, remobilisations and ossicular modelings, “spot-welding”; in this field the most argued area of applicability of LASER is the surgery of the otosclerosis. The otosclerosis treatment with surgical LASER started with Perkins and Di Bartolo...

Otosclerosis is a localized bone dystrophy of unknown etiology mainly involving the stapes. The hypothesis of a persistent infection by the measles virus was based on the inconstant detection of the virus by various methods, including reverse transcription-PCR (RT-PCR) of patients' stapes samples. The aim of this work was to investigate the presence of the measles virus in stapedial otosclerosi...

Background and Objectives Stapes surgery has been widely used to improve the conductive hearing loss caused by stapedial fixation. The purpose of this study is evaluate causes fixation using audiological results 100 stapes surgeries. Subjects Method We reviewed medical records consecutive surgeries between June 2011 December 2022. A total ears from 86 patients were included patient age ranged 6...

This retrospective study was performed in order to estimate the prevalence of clinical otosclerosis as a function of age and gender, characterize the hearing level in otosclerosis and describe the spontaneous progress of the disease as a function of age. Clinically based samples were obtained from an audiological department, including 556 subjects: n = 166 (30%) males and n = 390 (70%) females ...

Stapedotomy for otosclerosis presents particular anaesthesiology demands as the surgeon has to assess functional results during the operation, work with some bleeding, be ensured the collaboration of the patient, and limit the occurrence of intra- and post-operative symptoms (dizziness, nausea, vomiting and pain). Remifentanyl, a micro-opioid selective agonist characterised by short latency and...