total calcium with overt bone disease is hard to explain. The history of constipation, nocturia and polyuria, albeit mild, do suggest hypercalcaemia and it may be that the ionized calcium was elevated without the total calcium being raised. There are many points of similarity in the patient reported here with the case reported by Mather in 1953. His patient was a 39-year-old woman who had devel...

A case of oat cell carcinoma causing Cushing's syndrome and oncogenic hypophosphataemic osteomalacia is reported. The association of the two disorders in one patient is believed to be unique and this is the second reported case of oncogenic osteomalacia caused by oat cell carcinoma.

BackgroundRickets is a disorder due to impaired metabolism of bone mineralization which caused by low concentrations of extra-cellular calcium or phosphate. In children, hypophosphatemic rickets (HR) happen malabsorption of phosphate and increasing of renal tubular loss.Case Presentation We present the case of a 4-year-old girl who had medical history of HR with failure to thrive (FTT). Child h...

Vitamin D status relates to two bone diseases, osteomalacia and osteoporosis which arise from distinct pathophysiogical pathways. They can occur in children as well as adults. Osteomalacia or rickets arises from a delay in mineralization and can be caused by severe vitamin D deficiency where the key to curing osteomalacia is the endocrine action of circulating 1,25-dihydroxyvitamin D to normali...

Ethnic minorities in Britain having their origins in the West Indies, the Indian sub-continent (Asian), China and Africa consume diets which differ in varying degree from those of the indigenous population. These minority groups are in general well nourished and almost certainly share obesity with the host population as their commonest nutritional problem. Infantile rickets and iron deficiency ...

Vitamin D is integral for bone health, and severe deficiency can cause rickets in children and osteomalacia in adults. Although osteomalacia can cause severe generalized bone pain, there are only a few case reports of chest pain associated with vitamin D deficiency. We describe 2 patients with chest pain that were initially worked up for cardiac etiologies but were eventually diagnosed with cos...