SUMMARY Increasing detection of unruptured intracranial aneurysms, catastrophic outcomes from subarachnoid hemorrhage, and risks and cost of treatment necessitate defining objective predictive parameters of aneurysm rupture risk. Image-based computational fluid dynamics models have suggested associations between hemodynamics and intracranial aneurysm rupture, albeit with conflicting findings re...

Using high-speed confocal microscopy, we measure the particle positions in a colloidal suspension under large-amplitude oscillatory shear. Using the particle positions, we quantify the in situ anisotropy of the pair-correlation function, a measure of the Brownian stress. From these data we find two distinct types of responses as the system crosses over from equilibrium to far-from-equilibrium s...

Mechanical properties of polymer nanocomposites are significantly affected by spatial ordering of nanoparticles (NPs) which can be modified under shear flow fields. Polymer-grafted iron oxide NPs form strings, well-dispersed, and percolated anisotropic nanostructures depending on grafting density, and herein their mechanical properties under large oscillatory shear flows are reported. We show t...

Vasoactive drugs are known to affect impedance (pressure/flow) and vessel wall motion in arteries. The nonlinear theory of oscillatory flow in straight elastic vessels indicates that wall shear rate is affected by changes in impedance phase angle and wall motion. To test whether wall shear rate depends on impedance phase angle and wall motion in vivo, wall shear rate was measured in the abdomin...

We review recent advances in the generation of photonics materials over large areas and volumes, using the paradigm of shear-induced ordering of composite polymer nanoparticles. The hard-core/soft-shell design of these particles produces quasi-solid "gum-like" media, with a viscoelastic ensemble response to applied shear, in marked contrast to the behavior seen in colloidal and granular systems...

The mechanical properties of polymer nanocomposites are significantly affected by spatial ordering of nanoparticles (NPs) which can be modified under shear flow fields. Polymer-grafted iron oxide NPs form strings, well-dispersed, and percolated anisotropic nanostructures depending on grafting density, and herein their mechanical properties under large oscillatory shear flows are reported. We sh...

Large-amplitude oscillatory shear flow (LAOS) is a popular for studying the nonlinear physics of complex fluids. Specifically, the strain rate sweep (also called the strain sweep) is used routinely to identify the onset of nonlinearity. In this paper, we give exact expressions for the nonlinear complex viscosity and the corresponding nonlinear complex normal stress coefficients for the Oldroyd ...

BACKGROUND This study was aimed at developing a myocardial bridge-mural coronary artery simulative device and analyzing the relationship between shear stress on the mural coronary artery and atherosclerosis. METHODS A myocardial bridge-mural coronary artery simulative device was used to simulate experiments in vitro. In the condition of maintaining any related parameters such as system temper...

Vasoactive drugs are known to affect impedance (pressure/flow) and vessel wall motion in arteries. The nonlinear theory of oscillatory flow in straight elastic vessels indicates that wall shear rate is affected by changes in impedance phase angle and wall motion. To test whether wall shear rate depends on impedance phase angle and wall motion in vivo, wall shear rate was measured in the abdomin...