Abstract Aim The impact of COVID-19 on cancer presentations has been debated; this audit aimed to examine the stage at presentation head and neck (H&N) cancers regionally during pandemic compared identical time period 2019. Methods Retrospective data was collected across 3 hospitals in South West, identifying all H&N patients discussed Multi-disciplinary Team Meetings between 1st April-...

The following guidelines represent the current management at our center for the majority of patients presenting with cancer of the larynx, the oropharynx, or the oral cavity. These guidelines, which are applicable to at least 60% of our patients, show the usual sequence of events that occurs in the evaluation and treatment of these specific diseases. Many patients are eligible for participation...

Antrochoanal polyp is an infrequent nasal mass and is uncommon in elderly people. The case is presented of a 65-year-old man who developed a giant antrochoanal polyp which blocked the right maxillary sinus, nasal cavity, nasopharynx, oropharynx and hypopharynx. Endoscopic removal of the polyp as well as the base of the polyp was performed.

BACKGROUND There is convincing evidence that alcohol consumption increases the risk of cancer of the colorectum, breast, larynx, liver, esophagus, oral cavity and pharynx. Most of the data derive from studies that focused on the effect of moderate/high alcohol intakes, while little is known about light alcohol drinking (up to 1 drink/day). PATIENTS AND METHODS We evaluated the association bet...

Although the human papillomavirus (HPV) vaccine was introduced primarily as a cervical cancer prevention vaccine, HPV has a causal role in several types of cancer. This article reviews the epidemiological evidence for the role of HPV in human cancer, and describes Australian trends in these cancers. HPV is a necessary cause of cervical cancer. The currently vaccine-preventable subtypes of HPV 1...

BACKGROUND The incidence of oropharyngeal squamous cell carcinoma (OPSCC) caused by oncogenic human papillomavirus (HPV) is rising worldwide. HPV-OPSCC is commonly diagnosed by RT-qPCR of HPV E6 and E7 oncoproteins or by p16 immunohistochemistry (IHC). Droplet digital PCR (ddPCR) has been recently reported as an ultra-sensitive and highly precise method of nucleic acid quantification for biomar...

Oropharyngeal deposition of 3.5 μm particles inhaled through an elongated mouthpiece. K. Svartengren, M. Anderson, M. Svartengren, K. Philipson, P. Camner. © ERS Journals Ltd 1996. ABSTRACT: We previously studied the deposition of inhaled particles in the oropharynx of asthmatic patients, and found that a pharyngeal narrowing during inhalation seems to be one reason for high oropharyngeal depos...

BACKGROUND Human papillomavirus (HPV) is causally implicated in a subset of cancers of the upper aero-digestive tract (UADT). METHODS Associations between type-specific HPV antibodies were examined among 1496 UADT cancer case subjects and 1425 control subjects by estimating odds ratios (ORs) in logistic regression analyses adjusted for potential confounders. The agreement between serology and...

The most common malignancy to involve the oral cavity and oropharynx is squamous cell carcinoma (SCC). Because these oral cancers share an origin from the squamous epithelium, the pathology of oral SCC might be expected to be uniform and its diagnosis repetitive. In reality, the morphologic diversity in SCC, along with the propensity for reactive processes of the oral cavity to mimic SCC histol...