Contamination or transcutaneous absorption of organophosphates (OP) is rare and there exist only few reports of such manner of poisoning. We report four children from the same family in whom temporal proximity of the disease onset, a detailed interrogation of parents and exclusion of other clinical differentials, led to the diagnosis of transcutaneous intoxication with organophosphates (diazino...

A potentiometric enzyme biosensor for the direct measurement of organophosphate pesticides was developed. The basic element of this enzyme biosensor was a pH electrode modified with an immobilized organophosphorus hydrolase layer formed by cross-linking OPH with bovine serum albumin and glutaraldehyde. Organophosphorus hydrolase catalyzes the hydrolysis of organophosporus pesticides to release ...

Organophosphorus inhibitors of cholinesterases (commonly called organophosphates, OP) are used in industry as softening agents, hydraulic liquids, lubricant additives, plasticizers, antioxidants, and for antiflammable modifications. They are also used in veterinary or human medicine as drugs or chemicals for the study of nervous functions. They differ in their toxicity from practically non-toxi...

Organophosphorus nerve agents (OPAs) are a toxic class of synthetic compounds that cause adverse effects with many biological systems. Development methods for environmental remediation and passivation has been ongoing years. However, little progress made in therapeutic development exposure victims. Given the postexposure behavior OPA materials enzymes such as acetylcholinesterase (AChE), electr...

Treatment of head louse infection is primarily through topical insecticides. However, there is growing evidence of resistance. A representative population sample was tested using biochemical and molecular methods; it was shown that, in Wales, treatments containing pyrethroids are likely to be less effective in controlling head louse infection than those containing organophosphates.