ADVERTISEMENT RETURN TO ISSUEEditorialNEXTVirtual Issue: Organocatalysis in Polymer ScienceHaritz SardonHaritz SardonMore by Haritz Sardonhttps://orcid.org/0000-0002-6268-0916Cite this: Macromolecules 2022, 55, 10, 3769–3772Publication Date (Web):May 24, 2022Publication History Published online24 May 2022Published inissue 24 2022https://doi.org/10.1021/acs.macromol.2c00961Copyright © 2022 Ameri...

The Hydrogen Bond Enhanced Halogen (HBeXB) has recently been used to effectively improve anion binding, organocatalysis, and protein structure/function. In this study, we present the first systematic investigation of...

The formation of 1 out of 64 stereoisomers, i.e. controlling the creation of 6 stereocenters, of important optically active bicyclo[3.3.1]non-2-ene compounds, has been achieved using organocatalysis; the reaction proceeds with excellent stereocontrol and can be carried out with the generation of enantiopure products using chromatography-free procedures.

The title compound, C(16)H(20)O(3), contains a bicyclic ring system with two chiral centers. The crystal structure is stabilized by inter-molecular O-H⋯O hydrogen bonds. The absolute configuration was established by the stereo-selectivity of the asymmetric organocatalysis.

Nitroenynes are an interesting electrophile in asymmetric organocatalysis, due to the versatility of functional groups present its structure. This review covers organocatalytic examples using this and application for synthesis chiral heterocycles.

A 2021-es Kémiai Nobel-díj: organokatalízis, paradigmaváltás a szerves szintézisek és katalízis területén • The Nobel Prize in Chemistry 2021: Organocatalysis, Paradigm Shift Organic Syntheses and Catalysis