Abstract   Background: Squamous cell carcinoma (SCC) constitutes the main oral malignancy .   Parallel to better understanding of molecular and genetic patterns of tumor behavior, more precise correlation of tumor markers such as Epidermal Growth Factor (EGF) and Laminin-5 are sought to estimate macroscopic and microscopic tumor status .   Methods: We conducted a cross-sectional study collect...

calcifying epithelial odontogenic tumor is a rare odontogenic neoplasm. its occurrence in the maxillary sinus is very rare. maxillary tumors tend to be locally aggressive and may rapidly involve the surrounding vital structures.  we report a case of calcifying epithelial odontogenic tumor involving maxillary sinus in a 48 years old female patient with the oral mucosal involvement. the purpose o...

Malignant peripheral nerve sheath tumor (MPNST) is a rare malignant tumor that develops either from a preexisting neurofibroma or de novo. The cell of origin is believed to be the Schwann cell and possibly other nerve sheath cells. In this report, we describe a rare case of MPNST that arise from the socket of second left maxillary molar that has been already extracted in a young man. He was ref...

Background: Metastatic carcinomas to the upper jaw region are very rare and unfortunately occur in advanced stages of malignancies. Pancoast tumor is a challenging subset of lung carcinoma commonly followed by distant metastasis. Since the metastatic lesion of our patient was very huge and unusual, we decided to report the case. Case Presentation: Our patient was a middle-aged heavy smoker mal...

BACKGROUND 2'-Hydroxycinnamaldehyde (HCA) exerts antitumor activity against several human cancer cell lines. However, its antitumor activity in oral cancer has not been demonstrated. MATERIALS AND METHODS The antitumor activity of HCA was assessed in oral cancer cell lines and in a rat oral tumor model. RESULTS Cell cycle analysis confirmed that HCA showed anti-proliferative activity via ce...

The aim of this study was to provide pathological information pediatric oral lesions by retrospectively analyzing biopsy results from patients at the Seoul National University Dental Hospital. Biopsy all patients, aged 0 - 16 years, were collected files Department Oral Pathology, Hospital January 2000 April 2020. divided into 3 age groups: 5, 6 11 and 12 years. All classified three main categor...