BACKGROUND The strategies for the management of onychomycosis have changed since the availability of the newer generation of antifungal agents, particularly, itraconazole and terbinafine. Itraconazole (1-week pulse) therapy may have higher efficacy and an improved adverse-effects profile compared to the continuous therapy regimen. OBJECTIVE We performed a pharmacoeconomic evaluation of the mo...

Introduction: Recent epidemiological studies show that episodes due to non-albicans species of Candida (C) such as Candida tropicalis, C. glabrata, C, krusei, C. parapsilosis appear to be increasing in recurrent vulvovaginal candidiasis (RVVC). Increased use of the current antifungal drugs cause drug resistance among Candida species. In order to gain suitable antifungal therapy for this disease...

BACKGROUND Pityriasis versicolor (PV), also known as tinea versicolor, is caused by Malassezia species. This condition is one of the most common superficial fungal infections worldwide, particularly in tropical climates. PV is difficult to cure and the chances for relapse or recurrent infections are high due to the presence of Malassezia in the normal skin flora. This review focuses on the clin...

Recently, the taxonomy of Ochroconis (Ascomycota, Pezizomycotina, Venturiales, Sympoventuriaceae) has been revised with the recognition of an additional genus, Verruconis. Ochroconis comprises mesophilic saprobes that occasionally infect vertebrates which mostly are cold-blooded, while Verruconis contains thermophilic species which is a neurotrope in humans and birds. On the basis of molecular ...

Previous studies evaluating short-term itraconazole and terbinafine therapy for onychomycosis have varied in protocol and size; this double-blind study enabled a large-scale, standardized, direct comparison. Patients with toenail onychomycosis were randomized to itraconazole 200 mg daily (n = 146) or terbinafine 250 mg daily (n = 146) for 12 weeks, with a 36-week follow-up. Mycological cure rat...

Background: Dermatophytosis was a fungal infection caused by molds (dermatophytes). Dermatophytes are group of closely related filamentous fungi able to damage and utilize keratin found in the skin, hair, nails. Objective: To isolate species which cause resistant dermatophytosis, clinical types tinea, as well assess response different antifungal therapies.
 Patients Methods: Ninety-two pat...

of oral terbinafine (Lamisil; Sandoz) in the treatment of feline ringworm caused by. Fifteen cats infected with M canis were treated orally once daily with 30 mg/ kg of terbinafine over a 2-week period. Jul 16, 2015. Itraconazole is an antifungal drug that inhibits the growth of fungal organisms by. Overview Itraconazole for Dogs and Cats commonly known as "ringworm" and toenail infections. Rin...

Sir, Terbinafine is the most common antimycotic agent that can result in acute generalized exanthematous pustulosis (AGEP). The clinical features, laboratory findings and histopathology of AGEP are now well described. How­ ever the optimum management of this condition has not been agreed. We read with interest the recent case described by Beltraminelli et al. (1) and would like to report a furt...

We present the results of studies of the in vitro susceptibility of 52 isolates of Trichophyton rubrum and 40 of Trichophyton mentagrophytes to griseofulvin, terbinafine, itraconazole, ketoconazole, fluconazole and cyclopiroxolamine. All test strains were recovered from patients with toe nail onychomycosis and the minimum inhibitory concentration (MIC) of each antifungal against both species wa...