BACKGROUND Memantine is an N-methyl-D-Aspartate (NMDA) antagonist. By transferring acute postoperative pain, the NMDA channels may lead to active excess and neuropathic pain. Objectives: This study attempted to investigate the effect of preoperative use of single oral dose of memantine in controlling Dacryocystorhinostomy (DCR) postoperative pain. METHODS A double-blind clinical trial was con...

introduction : factors like preparing pediatric patients for anesthesia and surgery, separating them from parents, peculiarity of operation rooms and painful procedures such as injection usually produce anxiety and lack of cooperation in children. oral premedication with a sedative, anti-anxiety drug which has no major side effects can response to these challenges. materials and methods : in th...

BACKGROUND To compare oral midazolam (0.5 mg/kg) versus oral clonidine (4 μg/kg) as a premedication in pediatric patients aged between 2-12 years with regard to sedation and anxiolysis. METHODS Sixty pediatric patients belonging to the American Society of Anesthesiologists class I and II between the age group of 2-12 years scheduled for elective surgery were randomly allocated to receive eith...

OBJECTIVE Lumbar puncture (LP) essentially is a painful and stressful procedure, however indicated for diagnosis and therapeutic purposes. One way to reduce the anxiety is to administer an oral premedication. The aim of this study is to compare clinical effects of oral midazolam and oral promethazine in LP. MATERIALS & METHODS This prospective randomized controlled clinical trial study was pe...

Objective: The aim of study is to evaluate the preoperative sedative effects of intranasal dexmedetomidine as compared to oral midazolam as preanesthetic medication in children undergoing cardiac catheterization for diagnostic and/or therapeutic procedure. Design: Prospective, randomized, double-blind, controlled study. Method: 61 patients of either sex between the ages 2-10 years were recruite...

BACKGROUND This study aimed to compare sedative and analgesic effects of oral Midazolam and Ketamine on Bone Marrow aspiration (BMA) and Lumbar Puncture (LP). MATERIAL AND METHODS This study was a randomized clinical trial and was performed in Amirkola Hospital in north of Iran, Babol during 2011 and 2012 .The study population consisted of 40 patients who underwent the first time of diagnosti...

Purpose : The purpose of this study was to identify independent factors associated with prolonged recovery time after intravenous sedation for dental treatment in patients with intellectual disabilities. Methods : This study was designed as a prospective cohort study. Participants were patients with intellectual disabilities, for whom sedation for dental treatment was planned in Okayama Univers...

There is little evidence on the long-term effects of pharmacological management in children undergoing dental treatment. This study aimed to assess children's behavior in consecutive dental sessions following oral rehabilitation using different pharmacological regimens for behavioral control. Participants were preschoolers who were previously treated for caries under one of the following: no se...

Throughout the world there is considerable variation in the techniques used to manage anxious dental patients requiring treatment. Traditionally anxious or phobic dental patients may have been sent for general anaesthesia to allow dental treatment be undertaken. While this is still the case for the more invasive oral surgical procedures, such as wisdom teeth extraction, sedation in general dent...