Abstract Pemphigus Vulgaris is a chronic autoimmune mucocutaneous disease, in which oral lesions could be the first site observed, although skin and other mucous membranes may also be affected. Clinically, the lesions are characterized by many painful blisters that rapidly rupture resulting in erosions and/or multiple ulcers in the oral mucosa and skin, which can be difficult to differentiate f...

Pemphigus Vulgaris (PV) is an autoimmune intraepidermal blistering disorder of the skin and mucous membranes.1 Oral lesions have been reported as an initial manifestation of the disease in 50% of cases.2 A case of pemphigus vulgaris is hereby described occurring in a 55-year-old man with a chief complaint of 3-month history of chronic oral erosions and burning sensation. He had several superfic...

BACKGROUND Pemphigus vulgaris is a chronic inflammatory disease of skin, the etiology of which is not completely known. Despite the latter, anti-desmoglein antibodies play a proven role in the pathogenesis. Recent studies showed an etiologic effect for prolactin in the pemphigus vulgaris. This study aimed to quantify the correlation between serum prolactin levels and anti-desmoglein antibodies ...

INTRODUCTION Involvement of upper gastrointestinal tract in pemphigus vulgaris is not uncommon. AIM To study the involvement of upper gastrointestinal tract (UGIT) with the help of esophago-gastro-duodenoscopy (EGD) in patients of vesiculobullous dermatoses with emphasis on pemphigus vulgaris. METHODS Forty-two patients (M-22, F-20) with vesiculobullous dermatoses, diagnosed on the basis of...

BACKGROUND AND AIMS Oral pemphigus vulgaris is a chronic autoimmune mucocutaneous intraepi-thelial disease that primarily affects patients over the age of fifty, resulting in mucosal ulceration and is a potentially life-threatening disease. The purpose of this study was to investigate the efficacy of dap-sone in combination with systemic corticosteroids to treat the oral lesions of oral pemphig...

Pemphigus is rare in children, only 71 cases have been reported in literature. We report 2 cases of pemphigus vulgaris (13 and 15 years old) among 147 cases of pemphigus from Khouzestan who were admitted to the Department of Dermatology, Ahwaz Medical University between 1989-2001. The basis of diagnosis was clinical and histopathological findings in each patient. One patient was treated only wi...

Pemphigus vulgaris is an autoimmune bullous disorder characterized by the production of autoantibodies against the intercellular space of the epithelium. It has rarely been reported in association with inflammatory bowel disease. Ulcerative colitis is one of the forms of inflammatory bowel disease. A 62-year-old woman who had been treated for ulcerative colitis for 16 years developed pruritic b...

A clinicopalhological study of 70 cases of pemphigus observed over a span of four and a half years from January 1992 to June 1996 at the Sir J.J. Group of Hospitals and Grant Medical College, Mumbai is reported. Pemphigus vulgaris constituted the single largest group of 43 cases, followed by pemphigus foliaceus (25 cases) and pemphigus vegetans (2 cases). Majority of the cases were seen in the ...