Background: Oral lesions can affect people’s quality of life by impairment of chewing, swallowing and speech. These lesions may originate from epithelial or mesenchymal tissues. Malignant oral lesions could be life-threatening. Epidemiological data about oral lesions in our country is limited. Objective: This study was conducted to investigate the frequency of histopathologic features of oral ...

Oral delivery of a large dose or prolonged feeding of protein Ags induce systemic unresponsiveness most often characterized as reduced IgG and IgE Ab- and Ag-specific CD4(+) T cell responses. It remains controversial whether oral tolerance extends to diminished mucosal IgA responses in the gastrointestinal tract. To address this issue, mice were given a high oral dose of OVA or PBS and then ora...

INTRODUCTION Direct oral microscopy constitutes a novel, non-invasive diagnostic technique, which aids clinical examination of the oral cavity. The oral mucosa is examined at multiple magnifications and features such as sub-epithelial mucosal vessels, surface patterns, colour tone, transparency and the exact demarcation of mucosal lesions are estimated. The incidence of oral squamous cell carci...

Mucosal surfaces account for the vast majority of HIV transmission. In adults, HIV transmission occurs mainly by vaginal and rectal routes but rarely via oral route. By contrast, pediatric HIV infections could be as the result of oral route by breastfeeding. As such mucosal surfaces play a crucial role in HIV acquisition, and spread of the virus depends on its ability to cross a mucosal barrier...

BACKGROUND To know the prevalence of oral mucosal lesions among Pre-University students of Kodava population in Coorg District. This survey also aims to find out tobacco or other habits among students and related changes in the oral environment. MATERIALS & METHODS 900 PU students of Kodava population were included. 300 students from each taluk were randomly selected, after the consent. Quest...

Objective: To study the histomorphological changes of oral mucosa by observing the sections of lip buccal mucosae from patients with gastrointestinal cancer. Methods: Oral mucosae from 15 patients aged 61-80 years old who died of gastrointestinal cancer were sampled. Group A (n=10) had received high-dose chemoradiotherapy. Group B (n=10) were divided two subgroups. Group B1 (n=5) had gastrointe...

Pemphigus vulgaris (PV) is an autoimmune blistering disease affecting the skin and mucosa. It clinically presents as painful erosions, mainly in oral cavity, flaccid blisters erosions on skin. Steven-johnson syndrome/toxic epidermal necrolysis (SJS/TEN) a severe mucocutaneous drug hypersensitivity reaction characterized by painful, dusky, erythematous eruptions that often progress to blisters, ...

Contributors: 1Senior Lecturer, Department of Prosthodontics, Saraswati Dental College & Hospital, Lucknow, Uttar Pradesh, India; 2Reader, Department of Oral and Maxillofacial Surgery, Saraswati Dental College & Hospital, Lucknow, Uttar Pradesh, India; 3Senior Lecturer, Department of Oral & Maxillofacial Surgery, Saraswati Dental College & Hospital, Lucknow, Uttar Pradesh, India; 4Professor, De...

Mucosal immunization is advantageous over other routes of antigen delivery because it can induce both mucosal and systemic immune responses. Our goal was to develop a mucosal delivery vehicle based on bacteria generally regarded as safe, such as Lactobacillus spp. In this study, we used the Lyme disease mouse model as a proof of concept. We demonstrate that an oral vaccine based on live recombi...

BACKGROUND Despite the established link between oral human papillomavirus (HPV) infection and a subset of oropharyngeal squamous cell carcinoma (OSCC), little is known about the epidemiology of oral HPV infection among healthy adults in China. METHODS Oral swab specimens and questionnaires were collected from 5,410 individuals (ages 25-65 years). HPV DNA in oral exfoliated cells was tested by...