Amphotericin B (AmB) is a polyene antibiotic, widely used against life threatening systemic infections with fungi such as Candida albicans or Aspergillus fumigates as well as parasite such as Leishmania donovani. Until recently, AmB has been administered parenterally; however, this approach has been associated with significant infusion-related side effects and nephrotoxicity. Nevertheless, the ...

Objectives Periodontal diseases are one of the common oral diseases and microbial oral flora is one major factor responsible for it. Elimination of periodontal pathogens is particularly important in managing the periodontal state. This study aimed to assess the antibacterial effects of Nanosil, chlorhexidine (CHX) and probiotic mouthwashes on periodontal pathogens. Methods In this in-vitro stu...

Patients with heritable and idiopathic PVOD have few therapeutic options. On suspicion of immune dysregulation, methylprednisolone or oral prednisolone then mycophenolate mofetil was trialled in three cases, resulting clinical improvement/stability.https://bit.ly/376mwR9

Objective(s): We aimed to characterize the phenotype and genotype of Bacillus spp isolated from diabetic patients’ eyes, by studying the drug sensitivity patterns with a disc-diffusion method. Materials and Methods: Fifty eyes of 25 patients with type II diabetes mellitus, with at least 10 years of diabetes history, were included in the study. We analyzed the eyes for the presence of Bacillus ...

background: oral lesions are among the earliest clinical manifestations of human immunodeficiency (hiv) infection and are important in early diagnosis and for monitoring the progression to acquired immunodeficiency syndrome (aids). the purpose of this study was to determine the prevalence of oral lesions and their relationship with a number of factors in hiv/aids patients attending an hiv cente...

BACKGROUND Our previous studies showed that Salvianolic acid B (Sal B) inhibited 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamsters and such anti-cancer effects might be related to the inhibition of angiogenesis. This study was aimed to further investigate the anti-proliferative effect of Sal B on the most common type of oral cancer, oral squamous cell carcinoma (OSCC...

Background: Feeding intolerance is a common complication in preterm neonates and is responsible for prolonged hospitalization. This study aimed at assessing the effects of high-dose oral erythromycin on feeding intolerance in preterm infants.    Methods: A randomized, double blinded, placebo-controlled trial was performed during 2014 and 2015 (Tehran-Iran). Preterm neonates aged >14 ...