Reverse-biased silicon p-n junction arrays have been proposed as microdosimetry detectors. The tissue equivalence of such detectors in boron neutron capture therapy (BNCT) is discussed. A comparison of the range-energy relationships of H, He, C, and Li ions in tissue (ICRU-muscle) and silicon is given. A simple geometrical scaling (approximately 0.63) of linear dimensions is required to convert...

Boron Neutron Capture Therapy (BNCT) is a relatively safer technology for killing cancer cells, one of which the Glioblastoma multiforme. One main components BNCT equipment collimator functions as an exit point epithermal neutron particles that hit cells. In addition to experimental method, research can be carried out by modeling, including using MCNPX software based on Monte Carlo Method. This...

background: this study assessed the clinical usefulness of the solid phantom, which may compensate for the disadvantages of the water phantom, by comparing the radiological doses between the two depending on their depths. materials and methods: the experimental equipment used was a linear accelerator for medical use, water phantom, solid phantom, farmer type ion chamber and electrometer. the di...

Boron Neutron Capture Therapy (BNCT) is neutron radiotherapy used to treat tumours cells previously doped with Boron-10. This therapy requires an epithermal beam for the treatment of deep and a thermal shallow ones. Thanks recent high-current commercial accelerators, Accelerator-Based Sources (ABNS) are competitive option providing therapeutic beams in hospitals. In this work, field generated b...

Accelerator-based BNCT (Boron Neutron Capture Therapy) facilities are being studied, developed and constructed at many laboratories and hospitals, especially in Japan. In order to provide sufficient neutron flux in the epi-thermal energy region (0.5 ~ 10 keV), an intense proton beam accelerated with a cyclotron, linear accelerator (linac) or DC accelerator up to 2.5 ~ 30 MeV is directed to lith...

Boron neutron capture therapy (BNCT) is a binary treatment involving selective accumulation of boron carriers in a tumor followed by irradiation with a thermal or epithermal neutron beam. The neutron capture reaction with a boron-10 nucleus yields high linear energy transfer (LET) particles, alpha and (7)Li, with a range of 5 to 9 µm. These particles can only travel very short distances and rel...

PURPOSE To develop a procedure for the optimum patient positioning and immobilization during boron neutron capture therapy (BNCT) of glioblastoma multiforme (GBM) at the Brookhaven medical research reactor (BMRR). METHODS A replica of the treatment room in the BMRR was constructed to simulate patient position. A unique feature is a transparent opening in wall to simulate the location of the b...