Comment. The results suggest that in nonglaucomatous monkey globes, the CCT and the peripheral corneal thickness are not significantly correlated with the thickness of the lamina cribrosa in the center or at the periphery of the optic nerve head. They are also not associated with the thickness of the peripapillary sclera inside the optic nerve meninges or just outside the meninges. Confirming f...

We encountered a patient who suffered a head injury that translated to the optic nerves, leading to dramatic unilateral right optic nerve edema. The decedent was a 20-year-old unsecured passenger in a convertible. The car collided with a pickup truck. The patient survived for 8 h. At autopsy, a comminuted skull fracture involving the right frontal bone including the right orbital plate was foun...

1. Castiblanco CP, Adelman RA. Sympathetic ophthalmia. Graefes Arch Clin Exp Ophthalmol 2009;247:289-302. 2. Cha DM, Woo SJ, Ahn J, Park KH. A case of sympathetic ophthalmia presenting with extraocular symptoms and conjunctival pigmentation after repeated 23-gauge vitrectomy. Ocul Immunol Inflamm 2010;18:265-7. 3. Haruta M, Mukuno H, Nishijima K, et al. Sympathetic ophthalmia after 23-gauge tra...

PURPOSE Recent evidence strongly suggests that activated immunity occurs during the neurodegenerative process of glaucomatous optic neuropathy. Although activation of lamina cribrosa astrocytes has been identified in glaucomatous optic nerve head, their role on the activated immune responses seen in glaucoma patients is unknown. Here, the authors aimed to study the potential role of lamina crib...

Early diagnosis and treatment of glaucoma is important to reduce the risk of progressive and irreversible visual loss. The key to diagnosis is recognition of morphological changes to the optic nerve head and retinal nerve fiber layer, but in some patients, functional abnormalities are detected first. This review describes recent innovations with the potential to improve the early detection of g...

BACKGROUND Pseudo-doubling of the optic nerve head is a spectacular clinical entity, in which a lesion resembling an optic disk appears adjacent to the true optic disk. CASE REPORT A case of unilateral pseudo-doubling of the optic disk with bilateral optic nerve pits is presented. CONCLUSIONS The lesion is congenital, and represents a chorioretinal coloboma with optic disk involvement. Pseu...

The clinical and histopathological findings in the eyes of 2 patients with diffuse malignant melanoma of the choroid are described. The tumours were minimally elevated and nonpigmented in the peripapillary area, and both had an associated nonrhegmatogenous retinal detachment. Extension of the tumour into the region of the lamina choroidalis in each eye appeared to cause a localised constriction...

To the Editors: This letter reports a case illustrating an indirect traumatic optic neuropathy occurring from a dangerous pre-game sporting ritual. Our hope is that awareness of this activity and its danger may prevent its unnecessary recurrence. A 17-year-old male football player sustained a blunt traumatic head injury that occurred from a seemingly harmless and increasingly common activity, h...

PURPOSE To demonstrate ultrahigh-speed optical coherence tomography (OCT) imaging of the retina and optic nerve head at 249,000 axial scans per second and a wavelength of 1060 nm. To investigate methods for visualization of the retina, choroid, and optic nerve using high-density sampling enabled by improved imaging speed. METHODS A swept-source OCT retinal imaging system operating at a speed ...