background sphenoid sinus is surrounded by many vital vascular and nervous structures. in more than 20% of patients with chronic sinusitis, involvement of sphenoid sinus has been observed. besides, sphenoid sinus is an appropriate route to access anterior and middle cranial fossa in surgery. therefore, it is important to have an adequate knowledge about the contents of sphenoid sinus and its pr...

introduction hypoparathyroidism might cause various musculoskeletal findings, resembling spondyloarthropathies. case presentation we described a 52-year-old woman, diagnosed as a case of undifferentiated spondyloarthropathy for ten years, who was unresponsive to classic anti-inflammatory therapies. she developed anterior ischemic optic neuropathy and had elevated muscle enzymes during the cours...

ANTERIOR ISCHEMIC OPTIC NEUROPATHY (AION) Perioperative Arteritic Anterior Ischemic Optic Neuropathy (AAION) Hypotension Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) RADIATION OPTIC NEUROPATHY POSTERIOR ISCHEMIC OPTIC NEUROPATHY ISCHEMIC OPTIC DISC EDEMA WITH MINIMAL ISCHEMIC OPTIC NEUROPATHY IN SETTINGS OF DYSFUNCTION HEMODYNAMIC COMPROMISE Pre-AION Optic Disc Edema Spontaneous or T...

Introduction: Multiple sclerosis (MS) is a chronic, autoimmune, and inflammatory nervous system disease. It leads to the loss of myelin in the white matter of brain, spinal cord and optic nerves. As a chronic disease with sudden and unpredictable Side effects and complications of the disease will lead to disability and dependency in life. Causes neurologic symptoms and sig. The purpose of the p...

BACKGROUND AND PURPOSE Brain white matter is frequently affected in mitochondrial diseases; optic atrophy gene 1-autosomal dominant optic atrophy and Leber hereditary optic neuropathy are the most frequent mitochondrial monosymptomatic optic neuropathies. In this observational study, brain white matter microstructure was characterized by DTI in patients with optic atrophy gene 1-autosomal domin...

In multiple sclerosis, microstructural damage of normal-appearing brain tissue is an important feature of its pathology. Understanding these mechanisms is vital to help develop neuroprotective strategies. The visual pathway is a key model to study mechanisms of damage and recovery in demyelination. Anterograde trans-synaptic degeneration across the lateral geniculate nuclei has been suggested a...

localizing the optic disc (od) in retinal fundus images is of critical importance, since it is very similar to hard exudates (found in pathology) in color and brightness. because of the importance of od localization in clinical applications, many techniques have been developed. in this paper, we present the results obtained from two methods, correlation and least square, to approximate the opti...

background: neuromyelitis optica spectrum disease (nmosd) is a severe autoimmune demyelinating disorder of the central nervous system that throughout epidemiological data, it has not been completely determined. the aim of this study was to assess characteristics of nmosd patients in isfahan as one of the most prevalent cities for multiple sclerosis in iran. materials and methods: forty-five pat...

a 22 year-old woman presented with gradual visual loss in her right eye since 1990. medical and family histories were unremarkable. her visual acuity was 20/80 and 20/20 in right and left eyes respectively. slit lamp examination was quite normal with no relative afferent papillary defect.fundi of both eyes revealed subretinal lesion with optic nerve head involvement and subretinal fluid in papi...