DESCRIPTION Update of the 2004 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for glaucoma. METHODS The USPSTF reviewed evidence on the benefits and harms of screening for glaucoma and of medical and surgical treatment of early glaucoma. Beneficial outcomes of interest included improved vision-related quality of life and reduced progression of early asymptomatic glau...

A single-nucleotide polymorphism (SNP) rs4236601 at the CAV1/CAV2 locus is associated with primary open-angle glaucoma (POAG). Rs4236601 is common in Caucasians but rare in East Asians. Here we conducted a haplotype-tagging SNP analysis followed by replication in a total of 848 POAG cases and 1574 controls drawn from 3 cities in China and 1 city in Japan. Two SNPs, rs4236601 (odds ratio [OR] = ...

ous fluid by producing 0.5-mm holes. There is no reference given to this observation, therefore it is not clear how this observation was determined. The article states that the laser fiber is 200  m. It is unclear how this would create 500m ostia. On page 286, an aiming beam is mentioned in the Surgical Technique section. However, unless the AIDA laser system has been modified, and this is not...

We present the results of a double-blind trial comparing the efficacy of a single dose combination of guanethidine 3 % and adrenaline 0 5 % with that of adrenaline 1 % alone in reducing the intraocular pressure of eyes suffering from chronic open-angle glaucoma. The mean fall in ocular tension with the combined therapy was 10-67 mmHg, and with adrenaline 1% 6-31 mmHg, 24 hours after the commenc...

PURPOSE To evaluate the association between clinical parameters and the diagnosis of progression using VFI (Visual Field Index) and AGIS (Advanced Glaucoma Intervention Study) score in primary open angle glaucoma. METHODS Retrospective study of 517 visual fields of 78 eyes with primary open angle glaucoma analyzed with VFI and AGIS score. Clinical data registered included: age, sphere, pachim...

The aim of this study was to evaluate the role of Humphrey Matrix perimetry to better guide appropriate referral of at-risk individuals for glaucoma assessment. Fifty-two consecutive patients referred to a specialist glaucoma ophthalmology practice for an opinion about a new diagnosis of glaucoma were enrolled. Prior to assessment for presence of open-angle glaucoma, patients performed Humphrey...

The purpose of this study was to determine if a clinically feasible perimetric motion test utilizing random-dot kinematograms could identify glaucomatous visual field defects. Using a staircase procedure, an automated perimetric motion test and a larger foveally presented target were given to normal (n = 30), glaucoma suspects (n = 31) and primary open-angle glaucoma patients (n = 19). Motion t...

PURPOSE To evaluate the quality of life (QOL) of juvenile-onset primary open-angle glaucoma (JOAG) patients by using a utility-based assessment. METHODS QOL using time-tradeoff utility values was analyzed in 70 JOAG patients and compared with 108 adult-onset POAG patients. The relationships of utility values to parameters like age at diagnosis, visual acuity, mean deviation, number of medicat...

OBJECTIVE To investigate the correlation between central corneal thickness and outflow facility assessed by intraocular pressure peak and fluctuation during the water drinking test. METHODS Fifty-five newly diagnosed primary open-angle glaucoma patients submitted to central corneal thickness measurements and water drinking test were enrolled in this retrospective study.;. Patients were divide...

PURPOSE Our study aimed at investigating the extent to which saccadic eye movements are disrupted in patients with primary open-angle glaucoma (POAG). This approach followed upon the discovery of differences in the eye-movement behavior of POAG patients during the exploration of complex visual scenes. METHODS The eye movements of 8 POAG patients and 4 healthy age-matched controls were recorde...