The issue of fertility preservation in patients with cervical cancer is getting more and common considering the improved effectiveness early diagnosis treatment cancer. There a number evidence-based tactics available to diagnosed These have been proved effective include methods such as ovarian transposition; oocyte, embryo tissue cryopreservation. Nonetheless, there are no existing medical algo...

background: Many variations in oocyte and embryo grading make inter-laboratory comparisons extremely difficult. This paper reports the proceedings of an international consensus meeting on oocyte and embryo morphology assessment. methods: Background presentations about current practice were given. results: Theexpert panel developed a set of consensus points to define theminimumcriteria foroocyte...

the success of oocyte donation is influenced by multiple factors. we performed a retrospective analysis to evaluate prognostic factors in oocyte donation cycles. the main outcome measurements including recipient age, donor age, estradiol level in midcycle, the day of transfer and number of transferred embryos were not different in pregnant and non pregnant groups. endometrial pattern but not en...

Background: Since the sheep ‘Dolly’ was successfully cloned by somatic cell nuclear transfer (SCNT), the inefficiency of SCNT cloning and abnormality of cloned animals have been a focus of considerable controversy. Oocyte quality has been shown to contribute to poor somatic cloning and cell reprogramming efficiency with many factors affecting oocyte quality and developmental potential. It has b...

Background: Since the freezing method was offered, much effort has been done to improve the freezing conditions in different studies and the impact of different freezing methods and mediums on oocyte, embryo and ovarian tissues has been examined. Based on studies, minerals play an important role in oocyte maturation and subsequent embryo development. Vanadium is one of the minerals, which is ve...

Besides the established selection criteria based on embryo morphology and blastomere number, new parameters for embryo viability are needed to improve the clinical outcome of IVF and more particular of elective single-embryo transfer. Genome-wide gene expression in cumulus cells was studied, since these cells surround the oocyte inside the follicle and therefore possibly reflect oocyte developm...

The Drosophila oocyte, although often thought of as an undifferentiated cell, is in fact highly polarized, and the subcellular organization of the oocyte is critical for subsequent development of the embryo. Recent results show that cell-cell signaling between the germline and the somatic components of the egg chamber establish the dorsal-ventral and anterior-posterior axes of the egg and conse...

Citrinin is one of the mycotoxins and has been shown to have various toxic effects in animals and humans. Although previous study showed the toxic effects of citrinin on the female reproductive system, especially on oocyte maturation, however, the causes or mechanism of citrinin on oocyte quality is unclear. In present study we deeply investigated this topic. We found thatcitrinin toxin exposur...