Spam is commonly defined as unwanted e-mails and it became a global threat against e-mail users. Although, Support Vector Machine (SVM) has been commonly used in e-mail spam classification, yet the problem of high data dimensionality of the feature space due to the massive number of e-mail dataset and features still exist. To improve the limitation of SVM, reduce the computational complexity (e...

Motivation: In the exploding field of gene expression techniques such as DNA microarrays, there are still few general probabilistic methods for analysis of variance. Linear models and anova are heavily used tools in many other disciplines of scientific research. The usual F -statistic is unsatisfactory for microarray data, which explores many thousand genes in parallel, with few replicates. Res...

This research is to provide a solution of one-way ANOVA without using transformation when variances are heteroscedastic and group sizes are unequal. Parametric boothstrap test (Krishnamoorthy, Lu, & Mathew, 2007) has been shown to be competitive with many other methods when testing the equality of group means. We extend the parametric bootstrap algorithm to a multiple comparison procedure. Simu...

In last week’s lecture we came across an example, from Field (2013), about the drug Viagra, which is a sexual stimulant (used to treat impotence), which is supposed to make men better lovers. Suppose we tested this belief by taking three groups of people and administering one group with a placebo (such as a sugar pill), one group with a low dose of Viagra and one with a high dose. The dependent...

For one-way fixed effects ANOVA, it is well known that the conventional F test of the equality of means is not robust to unequal variances, and numerous methods have been proposed for dealing with heteroscedasticity. On the basis of extensive empirical evidence of Type I error control and power performance, Welch's procedure is frequently recommended as the major alternative to the ANOVA F test...

The independence assumption, although reasonable when examining cross-sectional data using single-factor experimental designs, is seldom verified by investigators. A Monte Carlo type simulation experiment was designed to examine the relationship between true Types I and II error probabilities in six multiple comparison procedures. Various aspects, such as patterns of means, types of hypotheses,...

91 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Statistical notes for clinical researchers: A one-way repeated measures ANOVA for data w...