Case: A 47-year-old Iranian man presented with a 3-month history of painful extremities lesions. The lesions began with an erythematous papule that progressively enlarged and ulcerated. His left calf was the first site of involvement. At the time we visited him, there were necrotic painful violaceous skin ulcers with a symmetrical distribution involving lower parts of distal limbs and his...

Helicobacter pylori (H. pylori), which increases the risk of gastric diseases, including digestive ulcers and gastric cancer, is highly prevalent in Asian countries. There is no doubt that eradication of the bacterium is effective as a treatment of digestive ulcer, but eradication aiming to reduce the gastric cancer risk is still controversial. Observational studies in Japan demonstrated that t...

This letter is about a 27 years old female with the diagnosis of Crohn's disease since July 2004, involving the duodenum, ileum and right colon. She was first treated with Mesalamine (1 g 3 id for 20 d, suspended because of the absence of efficacy), Prednisolone (four episode treatment, tapered), Azathioprine (since July 2004, up to 2.5 mg/Kg/d). She had four previous admissions at our hospital...

Presentamos el caso de una mujer de 72 años, sin alergias medicamentosas, con diabetes mellitus, hipercolesterolemia, hipertensión arterial, portadora de válvula de derivación ventrículo-peritoneal por hemorragia subaracnoidea tras rotura aneurismática, gastritis crónica atrófica que recibió tratamiento erradicador por Helicobacter pylori positivo y anemia ferropénica en tratamiento empírico de...

Background & Aim:  Ulcer index is one of the most common diseases among people. Current therapies include acid secretion inhibitors which have various side effects. Herbal medicines are considered as adjuvant therapy for this disease. Hydroalcoholic extract of Thymus daenensis has various components such as flavonoids which contribute to gastroprotection. Experimental: 35 <em...