Introduction: Indonesia is a country with large agricultural and industry, known to utilize various types of pesticides, as well several other industries uncontrolled pollution levels distributed across the nation. Besides, numerous studies have stated adverse effects chemicals substances used in daily life industrial waste on health living things, including humans. This study aimed determine i...

Objectives. To evaluate the sperm chromatin dispersion in men with infertility using first Russian kit. Methods. The study was conducted between July and August 2022. Study participants were 492 male volunteers aged 23 to 59 years which semen samples examined by GEMSTANDART–HaloSperm L&Q kit so-called Halo test. outcomes as a percentage DNA Fragmentation Index (DFI), %. results of test eval...

Background: The definition of World Health Organization (WHO) to the infertile couple is failure female get pregnancy in spite having regular sexual activity for at least 1 year without using any contraceptive methods, worldwide it estimated that 15 % reproductive-age couples are struggling with infertility.
 In many cases, infertility cannot be treated, new treatment options promising val...

There is concern that intracytoplasmic sperm injection (ICSI) may lead to offspring with a high frequency of chromosomal abnormalities. Accordingly, we studied spermatozoa sampled from eight infertile men with oligoasthenoteratozoospermia (OAT) by multi-colour fluorescence in-situ hybridization (FISH), using DNA probes for chromosomes 13, 18, 21, X and Y. Results were compared with those of spe...

Whether the 370-371insACA, 494T>C, and 1423C>T haplotype in ubiquitin-specific protease 26 (USP26) gene is associated with male infertility is controversial. To clarify this issue, we conducted a meta-analysis based on the most recent studies. Eligible studies were screened by using PubMed and Embase. Pooled odd ratio (OR) with 95% confidence interval (CI) was calculated with fixed effect model...

BACKGROUND/AIM This study aimed to find a link between sperm mitochondrial DNA mutations and male infertility in Pakistan. MATERIALS AND METHODS DNA from semen samples was extracted and amplified by PCR using 7.8-kb deletion-specific primers. The PCR products were separated on agarose gel, visualized under UV-illumination, and then photographed. The results were genotyped and the data were an...

BACKGROUND Polymorphism in the CTG triplet number in the myotonic dystrophy type 1 (DM1PK) gene has been proposed as being associated with idiopathic azoospermia. The aim of this study was to investigate whether the CTG trinucleotide amplification in the DM1PK gene is associated with male subfertility. METHODS We evaluated 107 subfertile patients, male partners of infertile couples, affected ...

Infertility affects 50 to 80 million people worldwide. Male factor is a cause of infertility in almost half of cases, mainly due to oligoasthenoteratozoospermia (OAT). With common diagnostic methods no cause can be found in approximately 30% of cases of male infertility due to OAT and these are considered idiopathic. Reactive oxygen species (ROS) play an important role in male infertility and a...

BACKGROUND Use of cellular phones emitting radiofrequency electromagnetic field (RF-EMF) has been increased exponentially and become a part of everyday life. This study aimed to investigate the effects of in vitro RF-EMF exposure emitted from cellular phones on sperm motility index, sperm DNA fragmentation and seminal clusterin (CLU) gene expression. MATERIALS AND METHODS In this prospective ...