BACKGROUND AND PURPOSE CHARGE syndrome is a genetic disorder resulting in the association of multiple congenital anomalies. Although a high prevalence of olfactory anomalies in CHARGE syndrome has been reported in autopsy and functional studies, to our knowledge, such anomalies have not been included among the diagnostic criteria, and their radiographic prevalence has not been assessed. The pur...

Parosmia is a common olfactory disorder. In this condition, odors are perceived in a different quality than usual. This distorted olfactory percept is typically reported to be unpleasant. Little is known about the pathophysiology of this phenomenon. Previous studies demonstrated smaller volumes of the olfactory bulbs in patients with parosmia compared to subjects without parosmia. In order to i...

We examined whether conversion to dementia can be predicted by self-reported olfactory impairment and/or by an inability to identify odors. Common forms of dementia involve an impaired sense of smell, and poor olfactory performance predicts cognitive decline among the elderly. We followed a sample of 1529 participants, who were within a normal range of overall cognitive function at baseline, ov...

Subjective halitosis is not confirmed by halitometer or third party individuals despite the patient insistently complaints malodor. This condition is named imaginary, delusional, pseudo, non-genuine, psychogenic, psychosomatic halitosis, halitophobia, body odor psychosis, depression, hypochondriasis, olfactory reference syndrome, chronic olfactory paranoid, syndrome, olfactory obsession, obsess...

It has been known for over 30 years that olfactory function is disordered in idiopathic Parkinson's disease (IPD). The severity and partial specificity of anosmia was not realized until recently, with the advent of more detailed analysis and sophisticated measurement. The olfactory vector hypothesis suggests that the causative agent for IPD enters the brain via the nasal route, but the reason f...

INTRODUCTION Olfaction may be related to food restriction and weight loss. However, reports regarding olfactory function in individuals with anorexia nervosa (AN) have been inconclusive. OBJECTIVE Characterize olfactory sensitivity and identification in female adolescents and young adults with first-episode AN and young females recovered from AN. METHODS We used the Sniffin' Sticks Odor Thr...

Background Alzheimer disease (AD) is a chronic disorder that affects millions of individuals worldwide. Olfactory dysfunction common symptom several neurological disorders including AD. can be an early alteration heralding the presence Studying pattern alterations in olfaction-related brain regions might help detection neurodegenerative diseases at earlier stage. Objectives this study are to as...

The human olfactory bulb (OB) is the first relay station of the olfactory pathway and may have the potential for postnatal neurogenesis in early childhood. In animals, chronic stress affects the OB and olfactory functioning. For humans, it has been shown that major depressive disorder is accompanied by reduced OB volume and reduced olfactory function. However, it is not clear if major stress in...

introduction: radiotherapy is a common treatment modality for patients with head and neck malignancies. as the nose lies within the field of radiotherapy of the head and neck, the olfactory fibers and olfactory receptors may be affected by radiation. the aim of this study was to evaluate changes in olfactory threshold in patients with head and neck malignancies who have received radiation to th...

Background Apnea of prematurity (AOP) is a developmental disorder that affects the premature newborns frequently. One of the new non-drug methods for controlling apnea attacks is olfactory stimulation. The aim of this study was to determine the effect of olfactory stimulation by vanilla on the rate of apnea attacks in neonates with AOP. Materials and Methods: This study is a single-blind random...