Background: To explore possible predictors of severe late ovarian hyperstimulation syndrome (SL-OHSS) in fresh embryo transfer cycles. Methods: We conducted a historical cohort study Chinese tertiary hospital from January 2017 to December 2019, with total 6931 women who had the first included. SL-OHSS was defined as symptoms OHSS occurring 12–17 days after ovulation triggering. Possible determi...

OBJECTIVE To compare the low-dose recombinant FSH and hMG protocols in treatment of patients with history of severe ovarian hyperstimulation syndrome (OHSS). DESIGN A prospective study on 22 patients with history of severe OHSS. Group A (n = 14) was treated with low-dose recombinant FSH 40 cycles and group B (n = 8) was treated with low-dose hMG in 26 cycles. SETTING The Egyptian IVF-ET Cen...

The following review aims to examine the available evidence to guide best practice in preventing ovarian hyperstimulation syndrome (OHSS). As it stands, there is no single method to completely prevent OHSS. There seems to be a benefit, however, in categorizing women based on their risk of OHSS and individualizing treatments to curtail their chances of developing the syndrome. At present, both A...

Ovarian hyperstimulation syndrome (OHSS) is a serious complication of assisted reproduction techniques using in vitro fertilization and intracytoplasmic sperm injection (IVF/ICSI). Its etiology has still not yet been fully resolved. Human chorionic gonadotrophin, administered exogenously as well as produced endogenously during pregnancy, is responsible for the onset of OHSS, and high levels of ...

BACKGROUND Management of established severe OHSS requires prolonged hospitalization, occasionally in intensive care units, accompanied by multiple ascites punctures, correction of intravascular fluid volume and electrolyte imbalance. The aim of the present study was to evaluate whether it is feasible to manage women with severe OHSS as outpatients by treating them with GnRH antagonists in the l...

Abstract Background Blood coagulation has been associated with ovulation and female infertility. In this study, the expression of tissue factor system was examined during in immature rats; correlation between ovarian hyperstimulation syndrome (OHSS) evaluated both rats human follicular fluids. Methods Ovaries were obtained at various times after chorionic gonadotropin (hCG) injection to investi...

BACKGROUND Ovarian hyperstimulation syndrome (OHSS) is a potentially life-threatening condition associated with increased vascular permeability. The vascular endothelial growth factor (VEGF) system and its receptors have been identified as the main angiogenic factors responsible for increased capillary permeability and are therefore discussed as crucial for the occurrence of OHSS. Recently, a n...

BACKGROUND Ovarian hyperstimulation syndrome (OHSS) typically occurs when ovaries are primed with FSH/LH and subsequently exposed to hCG. The ultimate pathophysiological step underlying this clinical picture is increased vascular permeability (VP). METHODS A search of the literature was carried out using PubMed and the authors' files. RESULTS In rodents and humans, the expression of vascula...

OBJECTIVE To report the management of a rare case of ovarian hyperstimulation syndrome (OHSS) induced by tamoxifen therapy for breast cancer in a 50-year-old woman. DESIGN Case report. SETTING Gynecology outpatient department of a university hospital. PATIENT(S) A 50-year-old premenopausal patient with a history of breast cancer was prescribed adjuvant treatment with tamoxifen. INTERVEN...