Rate constants for uptake and elimination of chemicals in organisms are often related to partition coefficients (typically the octanol-water partition coefficient). We show that the well-mixed one-compartment model for toxico-kinetics implies that the elimination rate is inversely proportional to the square root of the partition coefficient. When chemical exchange is limited by diffusion in the...

Jörg Durner, Andreas Thiel, and Peter Böger Lehrstuhl für Physiologie und Biochemie der Pflanzen, Universität Konstanz, D-7750 Konstanz, Bundesrepublik Deutschland Z. Naturforsch. 41c, 881 — 884 (1986); received May 26, 1986 Brassica napus, A trazine-Resistant M utants, Resistance Factors, Partition Coefficient Phenolic herbicides, being quite hydrophilic as compared to classical photosystem-II...

Many techniques for measurement of the tissue/gas partition coefficient are valid. Each has specific advantages and shortcomings. All the methods require suitable analytic equipment and means for controlling temperature. The disadvantages of a particular technique, the ability to cope with them and the availability of the necessary apparatus are the determining factors in choosing the best meth...

A vertex|matching-partition (V |M) of a simple graph G is a spanning collection of vertices and independent edges of G. Let vertex v ∈ V have weight wv and edge e ∈ M have weight we. Then the weight of V |M is w(V |M) = ∏ v∈V wv · ∏ e∈M we. Define the vertex|matching-partition function of G as W(G) = ∑ V |M w(V |M). In this paper we study this function when G is a path and a cycle. We generate ...

The permeability of lecithin bilayer membranes to nonelectrolytes is in reasonable agreement with Overton's rule. The is, Pd alpha DKhc, where/Pd is the permeability coefficient of a solute through the bilayer, Khc is its hydrocarbon:water partition coefficient, and D is its diffusion coefficient in bulk hydrocarbon. The partition coefficients are by far the major determinants of the relative m...

This report focus on phase behavior of polyethylene glycol (PEG)4000/ phosphate/ guanidine hydrochloride/ water system at different guanidine hydrochloride concentrations and pH. The binodal of the systems was displaced toward higher concentrations of the components with increasing guanidine hydrochloride concentrations. The partition coefficient of guanidine hydrochloride was near unity and in...

This report focus on phase behavior of polyethylene glycol (PEG)4000/ phosphate/ guanidine hydrochloride/ water system at different guanidine hydrochloride concentrations and pH. The binodal of the systems was displaced toward higher concentrations of the components with increasing guanidine hydrochloride concentrations. The partition coefficient of guanidine hydrochloride was near unity and in...

Background Myocardial extracellular volume is proportionate to partition coefficient (l). l can be measured by assessing the T1 relaxation time before and after injection of gadolinium. T1 and l might become clinically relevant parameters for prognostic assessment. The goal of that study is to assess the intersite reproducibility of T1 assessment and partition coefficient on phantom and on one ...

The halothane muscle/gas partition coefficients at 37 degrees C for 26 samples of eight different muscles from four horses were found to depend significantly on the fat content of the muscle sample with a regression coefficient of 1.913 (SEM 0.109) per per cent ether-extractable fat content. The blood/gas partition coefficients in 24 horses showed a significant dependence on plasma triglyceride...

The translational diffusion coefficient and the partition coefficient of a spin-labeled solute, di-t-butyl nitroxide, in an aqueous suspension of dipalmitoyl lecithin vesicles have been studied by electron spin resonance spectroscopy. When the lecithin is cooled through its phase transition temperature near 41 degrees C, some solute is "frozen out" of the bilayer, and the standard partial molar...