Objectives: Hyperlipidemia is a significant risk factor in the development of atherosclerosis and related diseases which are major health problem in many developed and developing countries that can lead to fatality due to the changes in lifestyle and dietary habits in this modern age. Methods: In the present study, the Ocimum gratissimum aqueous extract (OGE) was tested for the lowering effect ...

This research highlights the chemical composition, antioxidant, anti-inflammatory and anti-proliferative activities of essential oils from leaves of Ocimum basilicum, Ocimum americanum, Hyptis spicigera, Lippia multiflora, Ageratum conyzoides, Eucalyptus camaldulensis and Zingiber officinale. Essential oils were analyzed by gas chromatography-mass spectrometry and gas chromatography-flame ioniz...

The present study was designed to investigate the ameliorative potential of Ocimum sanctum and its saponin rich fraction in chronic constriction injury-induced neuropathic pain in rats. The chronic constriction injury was induced by placing four loose ligatures around the sciatic nerve, proximal to its trifurcation. The mechanical hyperalgesia, cold allodynia, paw heat hyperalgesia and cold tai...

Ocimum plants are traditionally used to manage HIV/AIDS in various African countries. The effects of Ocimum labiatum extract on HIV-1 protease (PR) and reverse transcriptase (RT) is presented here along with characterization of an identified bioactive compound, achieved through ¹H- and 13C-NMR. The extract's effect on HIV-1 replication was assessed by HIV-1 p24 antigen capture. Cytotoxicity of ...

Healthy adult albino rats of either sex of Wistar strain weighing 150 to 250 g were used after approval of the Institutional Ethics Committee. They were kept on standard pellet diet and were allowed free access to food and water. The doses of antitubercular drugs (isoniazid (I)-27 mg/kg/day, rifampicin (R)-54 mg/kg/day, pyrazinamide (Z)-135 mg/kg/day) were extrapolated from daily human dose usi...

BACKGROUND The present study aimed to evaluate the intracanal bacterial reduction promoted by chemomechanical preparation using three different herbal extracts named Ocimum sanctum (OS), Cinnamomum zeylanicum (CZ), Syzygium aromaticum (SA) against Enterococcus faecalis. MATERIAL AND METHODS Root canals from extracted teeth were contaminated with Enterococcus faecalis ATCC 29212 for 7 days and...

The effects of the aqueous and ethanolic extracts of Ocimum gratissimum (Linn) on the haematological indices and histology of the spleen of adult Wistar rats, as well as its antimicrobial properties were investigated in this study. Ocimum gratissimum (Linn) is widely distributed in tropical and warm temperate regions and is commonly called “fever plant”. Twenty five adult wistar rats with weigh...

INTRODUCTION Some species of Staphylococcus are often recognized as etiological agents of many animal and human opportunistic infections. This study is the first test of change in resistance of antibiotic activity by Croton campestris A. and Ocimum gratissimum L. against multiresistant strains of Staphylococcus aureus. OBJECTIVE In this study, the hexane and methanol extract of Croton campest...

Background. Opportunistic fungal infections like candidiasis are common in the oral cavity. In recent years Candida species have shown resistance against a number of synthetic drugs. This study assessed the antifungal activity of Centratherum anthelminticum and Ocimum sanctum seed oils against six common pathogenic Candida strains. Synergistic activity of the major oil components was also studi...