Comorbidity of obsessive-compulsive disorder (OCD) has been observed in about 15% of schizophrenic patients and has been associated with poor prognosis. Therefore, there is a need for specific treatment options for these patients (schizo-obsessive, ScOCD). This is an open, prospective study, aiming to test the efficacy of Ziprasidone (80-200mg/d) in ScOCD patients and comparing the response to ...

Thought control strategies are implicated in the development and maintenance of obsessive-compulsive disorder (OCD). Regarding one strategy - worry - extant data provide equivocal conclusions as to its relevance to OCD. The current study examined whether worry is an OCD-relevant thought control strategy using data from a large (N=376) nonclinical sample. This investigation tested whether worry ...

objective: the present study aimed to investigate the metacognitive model of obsessive-compulsive disorder (ocd), through a comparative study of thought fusion beliefs and thought control strategies between patients with ocd, depression, and normal people. methods: this is a causal-comparative study. about 20 patients were selected with ocd, and 20 patients with major depression disorder (mdd),...

INTRODUCTION Major depressive disorder (MDD) is the most frequent comorbid psychiatric condition associated with obsessive-compulsive disorder (OCD). This study aimed to evaluate the prevalence of current depression in OCD, differences in socio-demographic and clinical characteristics, and obsessive-compulsive symptoms between OCD patients with and without depression. Additionally, factors asso...

Objective: Obsessive compulsive disorder (OCD) is chronic psychiatric disorder with high rate of relapse during the course of illness. It is not well known which factors contribute for the chronicity of the illness, mainly because there are confounding factors as the medication effect. In this study we compared the difference of neurocognitive functions of the first-episode, medication-naive OC...

Objective: Obsessive compulsive disorder (OCD) is chronic psychiatric disorder with high rate of relapse during the course of illness. It is not well known which factors contribute for the chronicity of the illness, mainly because there are confounding factors as the medication effect. In this study we compared the difference of neurocognitive functions of the first-episode, medication-naive OC...

It has been proposed that certain Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Axis I disorders share overlapping clinical features, genetic contributions, and treatment response and fall within an "obsessive-compulsive" spectrum. Obsessive-compulsive personality disorder (OCPD) resembles obsessive-compulsive disorder (OCD) and other spectrum disorders in terms of pheno...

Objective: Obsessive compulsive disorder (OCD) is chronic psychiatric disorder with high rate of relapse during the course of illness. It is not well known which factors contribute for the chronicity of the illness, mainly because there are confounding factors as the medication effect. In this study we compared the difference of neurocognitive functions of the first-episode, medication-naive OC...

Psychiatric classificatory systems consider obsessions and compulsions as forms of anxiety disorder. However, the neurology of diseases associated with obsessive-compulsive symptoms suggests the involvement of fronto-striatal regions likely to be involved in the mediation of the emotion of disgust, suggesting that dysfunctions of disgust should be considered alongside anxiety in the pathogenesi...

We assessed correlates of obsessive-compulsive (OCPD), schizotypal (SPD) and borderline (BPD) personality disorders in 110 obsessive-compulsive disorder (OCD) patients. We found OCD patients with OCPD (20.9%) to exhibit higher rates of hoarding and bipolar disorders, increased severity of hoarding and symmetry, lower prevalence of unacceptable thoughts involving sex and religion and less non-pl...